Detailed information NTG0537238

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: I6K87_RS04130
• Genome accession: NZ_CP069892
• Coordinates: 829291..830643 (-)
• Length: 450 a.a.
• NCBI ID: WP_003027674.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain FDAARGOS_1357
• Function: repress competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	827649..828407	829291..830643	flank	884

Gene organization within MGE regions

Location: 827649..830643

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K87_RS04125 (I6K87_04125)	vicX	828485..829288 (-)	804	WP_003027672.1	MBL fold metallo-hydrolase	Regulator
I6K87_RS04130 (I6K87_04130)	micB	829291..830643 (-)	1353	WP_003027674.1	cell wall metabolism sensor histidine kinase VicK	Regulator

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51390.62 Da
• Isoelectric Point: 4.6926

>NTDB_id=537238 I6K87_RS04130 WP_003027674.1 829291..830643(-) (micB) [Streptococcus anginosus strain FDAARGOS_1357]
MIDNIRQFVVSKDFVFVLLILGFILVITLLSLENRRDNVRIRQLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide

• Length: 1353 bp

>NTDB_id=537238 I6K87_RS04130 WP_003027674.1 829291..830643(-) (micB) [Streptococcus anginosus strain FDAARGOS_1357]
ATGATTGATAATATTAGACAATTTGTTGTATCAAAAGATTTTGTATTTGTCTTACTCATTTTAGGATTTATTTTGGTGAT
TACCTTGCTTTCCTTGGAAAACCGACGTGATAATGTTCGTATTCGCCAATTGAATCAAAAAGTGAAAGACTTAATTGCAG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGCCCAGAAATTACGGATATTACTAATAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGTCTGTCGAGTATTTTATCCTATATGACGGACGGCGT
TCTTGCGACCAATCGTCGTGGGCAGATTATCATGATCAATGATATGGCGACCAAGCAGTTGGGGGTTAAAGAATCCGAAG
CACGAAAGATGAATATCTTAAAACTGCTGGATATCGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAG
CTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTTCGATTTGCCTTGATTCGGCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCAGTGCTGCATGATACAACGGAGCAGGAAAAAGAGGAACGTGAGCGGAGACTATTTGTTT
CTAATGTCAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAGGGTGCTTTGTCT
GAGCCAGTTGCACCAGATTTTATTAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGAATGGTTTCAGACTTGCTGAG
TTTGTCACGTATTGACAATGCTACCAGTCATTTGGATATTGAGCTGACAAATTTTACAGCTTTCATCACCTTTATTTTGA
ATCGTTTTGATAAAATCAGAAGTCAGAATGATGATAAGAAGTACGAAATTATTCGAGATTATCCTATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAAATTACGGTCAGTATGAAAACGACGGATACCCAAATGATTTTGTCTATATCAGATGAGGGCTTAGGGATTCCTAAAA
AAGATTTACCGAAAATTTTTGACCGCTTCTATCGTGTAGACAAAGCAAGAAGTCGTGCACAAGGTGGATCCGGATTAGGT
TTAGCTATTGCTAAGGAAATTATTAAGCAACATCACGGATTTATCTGGGCAAAGAGCGAGTATGGCAAAGGCTCAACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (95-198)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	81.321	97.556	0.793
vicK	Streptococcus mutans UA159	71.638	90.889	0.651