Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   I6J13_RS05935 Genome accession   NZ_CP068213
Coordinates   1226443..1227465 (-) Length   340 a.a.
NCBI ID   WP_037565861.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1156     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1221443..1232465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J13_RS05900 (I6J13_05900) - 1222464..1223663 (-) 1200 WP_006269979.1 acetate kinase -
  I6J13_RS05905 (I6J13_05905) comYH 1223710..1224663 (-) 954 WP_006269998.1 class I SAM-dependent methyltransferase Machinery gene
  I6J13_RS05910 (I6J13_05910) comGG 1224748..1225074 (-) 327 WP_003070783.1 competence type IV pilus minor pilin ComGG -
  I6J13_RS05915 (I6J13_05915) comGF/cglF 1225055..1225492 (-) 438 WP_006270001.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6J13_RS05920 (I6J13_05920) comGE/cglE 1225476..1225769 (-) 294 WP_006269989.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6J13_RS05925 (I6J13_05925) comYD 1225741..1226139 (-) 399 WP_006269995.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6J13_RS05930 (I6J13_05930) comYC 1226129..1226446 (-) 318 WP_006269985.1 competence type IV pilus major pilin ComGC Machinery gene
  I6J13_RS05935 (I6J13_05935) comYB 1226443..1227465 (-) 1023 WP_037565861.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6J13_RS05940 (I6J13_05940) comYA 1227407..1228348 (-) 942 WP_006269992.1 competence type IV pilus ATPase ComGA Machinery gene
  I6J13_RS05945 (I6J13_05945) - 1228418..1228783 (-) 366 WP_006269973.1 DUF1033 family protein -
  I6J13_RS05950 (I6J13_05950) glnA 1228971..1230317 (-) 1347 WP_006269977.1 type I glutamate--ammonia ligase -
  I6J13_RS05955 (I6J13_05955) - 1230356..1230715 (-) 360 WP_003070793.1 MerR family transcriptional regulator -
  I6J13_RS05960 (I6J13_05960) - 1230792..1231322 (-) 531 WP_006269975.1 aromatic acid exporter family protein -
  I6J13_RS05965 (I6J13_05965) - 1231462..1231746 (-) 285 WP_006269982.1 2'-5' RNA ligase family protein -
  I6J13_RS05970 (I6J13_05970) - 1231749..1231955 (-) 207 WP_006269988.1 hypothetical protein -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 38950.16 Da        Isoelectric Point: 9.6570

>NTDB_id=528053 I6J13_RS05935 WP_037565861.1 1226443..1227465(-) (comYB) [Streptococcus constellatus strain FDAARGOS_1156]
MQQDISLLSRQKRKKLSIVRQKKVVELLNNLFSSGFHLAEMIDFLKRSALLEKTYVEKMKEGLATGKPFSEIMASLGFSD
SVVTQLSLAELHGNLSLSLNKIEEYLENVSKVKKKLIEVATYPFILLIFLVFIMLGLRNYLLPQLERQNSATQLISQLPQ
IFLGSLGVVLVLLAIGFYWFRKSSKIVVFSFLARLPFCGTFIQAYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLIIEYGEVKSKLGCELEVYAQKTWEKFFSRINQAMNLVQPLVFVFVALV
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=528053 I6J13_RS05935 WP_037565861.1 1226443..1227465(-) (comYB) [Streptococcus constellatus strain FDAARGOS_1156]
ATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAGGCAGAAAAAAGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGCGGCTTTCATTTAGCAGAAATGATTGATTTTTTGAAGCGGAGTGCCCTGCTAGAAAAAA
CCTATGTGGAAAAGATGAAAGAGGGTTTAGCAACAGGAAAACCTTTTTCAGAAATTATGGCTAGTTTAGGATTTTCAGAT
AGTGTTGTCACCCAGCTTTCACTGGCAGAGCTACATGGGAATCTCTCACTCAGCCTGAATAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAGTCAAGAAAAAGTTAATTGAAGTAGCTACTTATCCATTCATTTTACTTATTTTTTTAGTATTCATTA
TGTTAGGGCTGCGAAATTATTTACTTCCGCAGTTAGAACGCCAAAATAGTGCAACGCAGCTGATTAGTCAGTTGCCGCAA
ATTTTTCTGGGTTCATTAGGAGTAGTCCTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTAGAAAAAGCTCAAAAATAGT
AGTGTTTAGCTTCTTGGCTCGACTTCCTTTTTGTGGAACTTTTATTCAAGCGTATTTGACAGCTTATTATGCGCGCGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTCAGTCAGATTTTTCAGATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGACTTAGAAGTTGCACTGCAAAATGGTCAGGAATTTTCCCAAGTGGTTAAACACTACCCGTTTTTTAA
AAAGGAATTGGGTTTGATAATTGAATACGGTGAAGTGAAATCCAAATTAGGGTGTGAATTAGAAGTTTATGCTCAAAAAA
CGTGGGAGAAGTTTTTTAGTCGGATCAATCAAGCTATGAACTTAGTGCAGCCGCTTGTCTTTGTTTTTGTGGCACTGGTT
ATTGTTTTATTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.529

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

70.118

99.412

0.697
  comGB/cglB Streptococcus mitis SK321

68.75

98.824

0.679
  comGB/cglB Streptococcus pneumoniae TIGR4

68.452

98.824

0.676
  comGB/cglB Streptococcus pneumoniae R6

68.452

98.824

0.676
  comGB/cglB Streptococcus pneumoniae Rx1

68.452

98.824

0.676
  comGB/cglB Streptococcus pneumoniae D39

68.452

98.824

0.676
  comYB Streptococcus mutans UA159

62.281

100

0.626
  comYB Streptococcus mutans UA140

61.988

100

0.624
  comGB Lactococcus lactis subsp. cremoris KW2

52.522

99.118

0.521