Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   I6J14_RS04990 Genome accession   NZ_CP068057
Coordinates   1026697..1027407 (-) Length   236 a.a.
NCBI ID   WP_003049952.1    Uniprot ID   A0A9X9SIG1
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1021697..1032407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS04975 (I6J14_04975) rnc 1023748..1024440 (-) 693 WP_003049954.1 ribonuclease III -
  I6J14_RS04980 (I6J14_04980) vicX 1024539..1025348 (-) 810 WP_115252716.1 MBL fold metallo-hydrolase Regulator
  I6J14_RS04985 (I6J14_04985) vicK 1025352..1026704 (-) 1353 WP_003049953.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6J14_RS04990 (I6J14_04990) vicR 1026697..1027407 (-) 711 WP_003049952.1 response regulator YycF Regulator
  I6J14_RS04995 (I6J14_04995) - 1027665..1028459 (+) 795 WP_003049951.1 amino acid ABC transporter ATP-binding protein -
  I6J14_RS05000 (I6J14_05000) - 1028459..1029259 (+) 801 WP_003049950.1 transporter substrate-binding domain-containing protein -
  I6J14_RS05005 (I6J14_05005) - 1029273..1029974 (+) 702 WP_003049949.1 amino acid ABC transporter permease -
  I6J14_RS05010 (I6J14_05010) - 1029989..1030636 (+) 648 WP_003049948.1 amino acid ABC transporter permease -
  I6J14_RS05015 (I6J14_05015) - 1030699..1031232 (-) 534 Protein_997 IS3 family transposase -
  I6J14_RS05020 (I6J14_05020) - 1031410..1032405 (-) 996 WP_115252715.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27029.90 Da        Isoelectric Point: 4.9981

>NTDB_id=526722 I6J14_RS04990 WP_003049952.1 1026697..1027407(-) (vicR) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEDEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=526722 I6J14_RS04990 WP_003049952.1 1026697..1027407(-) (vicR) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGAAAAAAATACTGATTGTGGATGATGAGAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGTGAAGCTGTTACCGTGTTTGAAGACGAAAAACCGGATTTAATTATTCTTGATTTGA
TGTTACCGGAATTGGACGGTCTTGAAGTGGCCAAAGAAATCCGTAAAACCAGTCATGTGCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGCCTTGAAATTGGAGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAAGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACTATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTGGACGTGACAGTTCGCCGCCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377