Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I6J14_RS04985 Genome accession   NZ_CP068057
Coordinates   1025352..1026704 (-) Length   450 a.a.
NCBI ID   WP_003049953.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1020352..1031704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS04975 (I6J14_04975) rnc 1023748..1024440 (-) 693 WP_003049954.1 ribonuclease III -
  I6J14_RS04980 (I6J14_04980) vicX 1024539..1025348 (-) 810 WP_115252716.1 MBL fold metallo-hydrolase Regulator
  I6J14_RS04985 (I6J14_04985) vicK 1025352..1026704 (-) 1353 WP_003049953.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6J14_RS04990 (I6J14_04990) vicR 1026697..1027407 (-) 711 WP_003049952.1 response regulator YycF Regulator
  I6J14_RS04995 (I6J14_04995) - 1027665..1028459 (+) 795 WP_003049951.1 amino acid ABC transporter ATP-binding protein -
  I6J14_RS05000 (I6J14_05000) - 1028459..1029259 (+) 801 WP_003049950.1 transporter substrate-binding domain-containing protein -
  I6J14_RS05005 (I6J14_05005) - 1029273..1029974 (+) 702 WP_003049949.1 amino acid ABC transporter permease -
  I6J14_RS05010 (I6J14_05010) - 1029989..1030636 (+) 648 WP_003049948.1 amino acid ABC transporter permease -
  I6J14_RS05015 (I6J14_05015) - 1030699..1031232 (-) 534 Protein_997 IS3 family transposase -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51476.02 Da        Isoelectric Point: 5.5557

>NTDB_id=526721 I6J14_RS04985 WP_003049953.1 1025352..1026704(-) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=526721 I6J14_RS04985 WP_003049953.1 1025352..1026704(-) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGACTAGAGATATCATCGGGAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAATGAGAAGGCGGACATTGAATTGATGGAACTGGCAGATCAGTTAAATGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTTAATCTGACCAAGGAGCAGG
CTCTTGAAAAGAACATTACCGATTTGCTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGTTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCCTCAAG
GAAGATATTGCCCCAAGTTTTATCAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGAATGATTTCTGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTTGAGATGACCAATTTCACAGCTTTTATGACGTCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGATTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCAATTAAATACTCTCCTGA
TGGTGGAAAGATTACTGTTCGCATGAAAACAACAGACACGCAATTGATTATTTCCATCTCAGACCAAGGTTTAGGCATTC
CGAAGAAGGACCTGCCCCTTATTTTTGACCGTTTTTACCGAGTGGACAAGGCAAGAAGTCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631