Detailed information NTG0052634

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: B657_RS18795
• Genome accession: NC_018520
• Coordinates: 3576820..3577977 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis QB928
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3571820..3582977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B657_RS18765 (B657_35440)	yvyF	3572073..3572492 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
B657_RS18770 (B657_35450)	comFC	3572566..3573288 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
B657_RS18775 (B657_35460)	comFB	3573252..3573548 (-)	297	WP_003227989.1	late competence protein ComFB	-
B657_RS18780 (B657_35470)	comFA	3573608..3574999 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
B657_RS18785 (B657_35480)	fakBA	3575105..3575950 (-)	846	WP_003244125.1	DegV family protein	-
B657_RS18790 (B657_35490)	degU	3576048..3576737 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
B657_RS18795 (B657_35500)	degS	3576820..3577977 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
B657_RS18800 (B657_35510)	yvyE	3578194..3578847 (+)	654	WP_003227979.1	YigZ family protein	-
B657_RS18805 (B657_35520)	tagV	3578847..3580022 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
B657_RS18810 (B657_35530)	tagO	3580095..3581171 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
B657_RS18815 (B657_35540)	tuaH	3581316..3582509 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=52634 B657_RS18795 WP_003227983.1 3576820..3577977(-) (degS) [Bacillus subtilis QB928]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=52634 B657_RS18795 WP_003227983.1 3576820..3577977(-) (degS) [Bacillus subtilis QB928]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1