Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   JJN14_RS05815 Genome accession   NZ_CP067992
Coordinates   1197283..1197933 (-) Length   216 a.a.
NCBI ID   WP_201058111.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1192283..1202933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS05800 (JJN14_05800) - 1192897..1194081 (-) 1185 WP_201058108.1 hypothetical protein -
  JJN14_RS05805 (JJN14_05805) - 1194085..1194672 (-) 588 WP_201058109.1 ABC transporter ATP-binding protein -
  JJN14_RS10095 - 1194693..1194917 (-) 225 Protein_1096 hypothetical protein -
  JJN14_RS05810 (JJN14_05810) comEC/celB 1195059..1197299 (-) 2241 WP_201058110.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  JJN14_RS05815 (JJN14_05815) comEA/celA/cilE 1197283..1197933 (-) 651 WP_201058111.1 helix-hairpin-helix domain-containing protein Machinery gene
  JJN14_RS05820 (JJN14_05820) - 1198000..1198569 (-) 570 WP_201058112.1 GNAT family N-acetyltransferase -
  JJN14_RS05825 (JJN14_05825) - 1198655..1199659 (-) 1005 WP_201058113.1 PhoH family protein -
  JJN14_RS05830 (JJN14_05830) - 1199745..1199960 (-) 216 WP_201058114.1 YozE family protein -
  JJN14_RS05835 (JJN14_05835) cvfB 1199969..1200823 (-) 855 WP_001095445.1 RNA-binding virulence regulatory protein CvfB -
  JJN14_RS05840 (JJN14_05840) frr 1200883..1201440 (-) 558 WP_001262225.1 ribosome recycling factor -
  JJN14_RS05845 (JJN14_05845) pyrH 1201449..1202186 (-) 738 WP_000002996.1 UMP kinase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23153.43 Da        Isoelectric Point: 7.9589

>NTDB_id=526162 JJN14_RS05815 WP_201058111.1 1197283..1197933(-) (comEA/celA/cilE) [Streptococcus mitis strain S022-V7-A3]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQIPVKETNLQGEVAAVSKVSSTEKDVKREEKDESVEQDVITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAASQQTGSGTASSKNKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHRESNGKFKSVDELKKVSGIGAKTIEKLKDYVTAD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=526162 JJN14_RS05815 WP_201058111.1 1197283..1197933(-) (comEA/celA/cilE) [Streptococcus mitis strain S022-V7-A3]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAATACCTGTTAAAGAGACGAATTTACAGGGAGAAGTTGCAGCTGTTTCCAAGGTTT
CATCGACCGAAAAGGATGTGAAGAGGGAAGAGAAGGACGAATCGGTTGAACAAGATGTGATTACAGTAGATGTGAAAGGC
GCTGTTAAATCACCAGGGATTTATGACTTGCCAGTAGGTAGTCGGGTCAATGATGCTGTTCAAAAGGCGGGTGGCTTGAC
AGAGCAAGCAGACAGCAAATCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTCTACGTTCCAACTAAGGGAG
AAGAAGCAGCTAGTCAACAGACTGGTTCTGGGACAGCTTCTTCAAAGAACAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAGCTCAAGCAGGTCAAGGGTCTGGGTGGCAAACGAGCTCAGGATATTATCGACCATCGTGAATCAAATGG
GAAATTCAAGTCGGTTGATGAACTCAAGAAGGTTTCTGGCATTGGTGCTAAAACGATAGAAAAGCTAAAAGACTATGTTA
CAGCGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

93.056

100

0.931
  comEA/celA/cilE Streptococcus mitis NCTC 12261

91.667

100

0.917
  comEA/celA/cilE Streptococcus pneumoniae Rx1

90.741

100

0.907
  comEA/celA/cilE Streptococcus pneumoniae D39

90.741

100

0.907
  comEA/celA/cilE Streptococcus pneumoniae R6

90.741

100

0.907
  comEA/celA/cilE Streptococcus mitis SK321

89.815

100

0.898
  comEA Lactococcus lactis subsp. cremoris KW2

41.256

100

0.426