Detailed information NTG0526161

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: JJN14_RS05810
• Genome accession: NZ_CP067992
• Coordinates: 1195059..1197299 (-)
• Length: 746 a.a.
• NCBI ID: WP_201058110.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain S022-V7-A3
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1190059..1202299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JJN14_RS05780 (JJN14_05780)	-	1190972..1191352 (-)	381	WP_000157153.1	VOC family protein	-
JJN14_RS05785 (JJN14_05785)	rplT	1191411..1191770 (-)	360	WP_000124834.1	50S ribosomal protein L20	-
JJN14_RS05790 (JJN14_05790)	rpmI	1191822..1192022 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
JJN14_RS05795 (JJN14_05795)	infC	1192055..1192585 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
JJN14_RS05800 (JJN14_05800)	-	1192897..1194081 (-)	1185	WP_201058108.1	hypothetical protein	-
JJN14_RS05805 (JJN14_05805)	-	1194085..1194672 (-)	588	WP_201058109.1	ABC transporter ATP-binding protein	-
JJN14_RS10095	-	1194693..1194917 (-)	225	Protein_1096	hypothetical protein	-
JJN14_RS05810 (JJN14_05810)	comEC/celB	1195059..1197299 (-)	2241	WP_201058110.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
JJN14_RS05815 (JJN14_05815)	comEA/celA/cilE	1197283..1197933 (-)	651	WP_201058111.1	helix-hairpin-helix domain-containing protein	Machinery gene
JJN14_RS05820 (JJN14_05820)	-	1198000..1198569 (-)	570	WP_201058112.1	GNAT family N-acetyltransferase	-
JJN14_RS05825 (JJN14_05825)	-	1198655..1199659 (-)	1005	WP_201058113.1	PhoH family protein	-
JJN14_RS05830 (JJN14_05830)	-	1199745..1199960 (-)	216	WP_201058114.1	YozE family protein	-
JJN14_RS05835 (JJN14_05835)	cvfB	1199969..1200823 (-)	855	WP_001095445.1	RNA-binding virulence regulatory protein CvfB	-
JJN14_RS05840 (JJN14_05840)	frr	1200883..1201440 (-)	558	WP_001262225.1	ribosome recycling factor	-
JJN14_RS05845 (JJN14_05845)	pyrH	1201449..1202186 (-)	738	WP_000002996.1	UMP kinase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84885.17 Da
• Isoelectric Point: 9.5218

>NTDB_id=526161 JJN14_RS05810 WP_201058110.1 1195059..1197299(-) (comEC/celB) [Streptococcus mitis strain S022-V7-A3]
MLQRIKTFPVPLIYLSFLLLWLYYAIFSASYIALLGFVFLLVCLFIQFSWKSASKVLVLCGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKHDGRIFQVYYKLQSEEEKEAFQTLIDLHEIELEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTINIKKIQSLQKVGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLWQKLLAQHGYKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYDFILTMTSKEGEGLKAVTRESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLAFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGMIRFVSQVASRPLVFGQPNAWLLVLLLISLALVYDLRKNIKRLAVLSLLITGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKIILIDVGGKAESSKKIEKWQEKTTTSNAQRSLIPYLKGRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKEFVAELQATQTKVRSVTAGENLPIFGSRLEVLSPRKIGNGNHEDSLVLYGKL
LDKNFLFTGNLEEKGEKDLLRQYPDLEVDVLKASQHGSKKLSSSAFLEQLKPEFTLISVGKNNRTKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGWNRWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=526161 JJN14_RS05810 WP_201058110.1 1195059..1197299(-) (comEC/celB) [Streptococcus mitis strain S022-V7-A3]
ATGTTACAGCGGATTAAGACTTTCCCTGTTCCCCTAATCTATCTGAGTTTTCTATTGCTCTGGCTTTACTACGCCATTTT
TTCAGCATCCTATATCGCACTGCTAGGCTTCGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTTCTTGGAAATCTGCTA
GCAAAGTTCTAGTGCTTTGTGGAATTTTTGGATTCTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
TTGGCGGATTCTGTTGAAAGGGTGCGGATTTTGCCTGACACTATTAAGGTCAATGGTGATAGTCTGTCCTTTCGTGGTAA
GCATGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAACTTTAATAGACC
TTCATGAGATAGAACTTGAAGGAAAACTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGTTTTGACTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTATCAATATCAAAAAAATTCAGTCACTTCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGCTTACGTCGAAAGGCTGTAGTTTGGATCAAGACGCACTTTCCAGATCCTATGCGCAATTACATGA
CGGGGCTTCTATTAGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCTAGTCTAGGAATTATCCATCTT
TTTGCCTTGTCGGGCATGCAGGTAGGCTTTTTCATGGATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGCCTGACAGGGTTTTCAGCATCGGTCATTCGCAGTC
TTTGGCAAAAACTATTGGCTCAACATGGCTATAAGGGATTAGATAATTTTGCCCTGACTGTGCTTGTTCTCTTTATCGTC
ATGCCTAACTTTTTCCTGACTGCAGGAGGAGTTTTGTCCTGCGCTTATGATTTTATCTTGACTATGACCAGCAAAGAAGG
AGAGGGCCTAAAGGCTGTGACCAGAGAAAGTCTAGTCATTTCCTTGGGAATATTGCCCATTCTGTCCTTCTATTTTGCGG
AATTTCAACCTTGGTCCATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGGCCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCATTTCTCTATCCAGTCATTCAGCTTAATTTTATTTTTGAATGGTTGGAGGGGATGATTCGCTTTGT
ATCACAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATGCATGGCTTTTAGTTTTATTGTTAATTTCCTTGGCTT
TAGTATATGATTTGAGGAAAAACATTAAAAGGCTAGCAGTATTGAGCTTATTGATTACGGGTCTCTTTTTCTTGACCAAG
CATCCACTGGAAAATGAAATTACCATGCTGGATGTGGGGCAAGGCGAAAGTATTTTCCTACGGGATGTAACTGGTAAGAT
CATTCTTATAGATGTCGGCGGCAAGGCAGAATCTAGCAAGAAAATCGAAAAATGGCAAGAAAAGACGACGACAAGCAACG
CCCAGCGAAGCTTGATTCCCTATCTAAAAGGTCGAGGAGTAGCCAAGATTGACCAGCTGATTTTAACAAATACAGACAAG
GAGCATGTTGGAGATTTGTTGGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGTAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCAACTCAAACCAAGGTGCGTAGTGTGACAGCAGGAGAGAACTTGCCAATTTTTG
GAAGTCGGTTAGAAGTCCTGTCTCCAAGGAAAATTGGAAATGGAAATCATGAAGATTCCCTGGTTTTGTATGGAAAACTC
TTGGATAAAAACTTTCTTTTCACAGGAAATTTGGAGGAAAAAGGAGAGAAGGACTTGCTGAGGCAATATCCTGACCTAGA
GGTGGATGTTTTGAAAGCTAGCCAACATGGCTCTAAAAAATTATCAAGTTCAGCCTTTTTAGAACAGCTCAAACCAGAGT
TTACTCTCATTTCAGTTGGAAAGAACAATCGAACGAAACTCCCCCATCAGGAAACCTTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAGGGAGCTATACGCTTTAAAGGGTGGAATAGATGGAAAATCGAAAGCGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Domain of unknown function (DUF4131) (DUF4131) (30-177)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	92.761	100	0.928
comEC/celB	Streptococcus mitis NCTC 12261	92.215	99.866	0.921
comEC/celB	Streptococcus pneumoniae TIGR4	91.019	100	0.91
comEC/celB	Streptococcus pneumoniae D39	90.885	100	0.909
comEC/celB	Streptococcus pneumoniae Rx1	90.885	100	0.909
comEC/celB	Streptococcus pneumoniae R6	90.885	100	0.909
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44