Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   JJN14_RS05130 Genome accession   NZ_CP067992
Coordinates   1053230..1053937 (-) Length   235 a.a.
NCBI ID   WP_000722072.1    Uniprot ID   A0A3R9LLL2
Organism   Streptococcus mitis strain S022-V7-A3     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1048230..1058937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS05115 (JJN14_05115) - 1049084..1050970 (-) 1887 WP_201058012.1 Eco57I restriction-modification methylase domain-containing protein -
  JJN14_RS05120 (JJN14_05120) vicX 1051077..1051886 (-) 810 WP_201058013.1 MBL fold metallo-hydrolase Regulator
  JJN14_RS05125 (JJN14_05125) micB 1051888..1053237 (-) 1350 WP_084863416.1 cell wall metabolism sensor histidine kinase VicK Regulator
  JJN14_RS05130 (JJN14_05130) micA 1053230..1053937 (-) 708 WP_000722072.1 response regulator YycF Regulator
  JJN14_RS05135 (JJN14_05135) mutY 1053992..1055167 (-) 1176 WP_201058014.1 A/G-specific adenine glycosylase -
  JJN14_RS05140 (JJN14_05140) pta 1055250..1056224 (-) 975 WP_201058016.1 phosphate acetyltransferase -
  JJN14_RS05145 (JJN14_05145) - 1056268..1057164 (-) 897 WP_201058018.1 RluA family pseudouridine synthase -
  JJN14_RS05150 (JJN14_05150) - 1057161..1057979 (-) 819 WP_201058019.1 NAD kinase -
  JJN14_RS05155 (JJN14_05155) - 1057963..1058634 (-) 672 WP_201058021.1 GTP pyrophosphokinase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27107.90 Da        Isoelectric Point: 4.6177

>NTDB_id=526155 JJN14_RS05130 WP_000722072.1 1053230..1053937(-) (micA) [Streptococcus mitis strain S022-V7-A3]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDNQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=526155 JJN14_RS05130 WP_000722072.1 1053230..1053937(-) (micA) [Streptococcus mitis strain S022-V7-A3]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
GGTTGTAACTGCTTTTAATGGCCGTGAAGCGCTAGAACAATTTGAAGCAGAGCAGCCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTCTAGAAGTTGCTAAGACTATTCGCAAGACAAGTAGTGTACCTATTATCATGCTTTCTGCC
AAAGACAGTGAATTTGATAAGGTTATCGGTTTAGAGCTTGGGGCGGATGACTATGTGACAAAACCCTTCTCGAATCGTGA
ATTGCAGGCGCGTGTTAAAGCTCTTCTTCGTCGTACGGACTTGGTTTCTGTAGATAATCAAGAGTCTGATGAAAAGAAAA
CCCAACCCTTGCAAATTGGGGACTTGGAGATTGTTCCAGATGCCTATGTTGCTAAAAAATATGGTGAAGAACTAGACTTA
ACCCACCGTGAATTTGAGCTTTTGTATCACTTGGCGTCTCATATCGGTCAAGTAATTACGCGTGAACACTTGCTTGAAAC
TGTCTGGGGTTATGATTATTTCGGAGATGTTCGAACAGTCGACGTAACTATCAGACGTTTGCGTGAGAAGATTGAAGACA
CGCCAAGTCGTCCAGAATATATTCTAACACGTCGCGGTGTTGGTTATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9LLL2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

94.017

99.574

0.936
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

44.589

98.298

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.723

98.298

0.43
  scnR Streptococcus mutans UA159

38.034

99.574

0.379