Detailed information NTG0526154

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: JJN14_RS05125
• Genome accession: NZ_CP067992
• Coordinates: 1051888..1053237 (-)
• Length: 449 a.a.
• NCBI ID: WP_084863416.1
• Uniprot ID: A0A1X1KE01
• Organism: Streptococcus mitis strain S022-V7-A3
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1046888..1058237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JJN14_RS05115 (JJN14_05115)	-	1049084..1050970 (-)	1887	WP_201058012.1	Eco57I restriction-modification methylase domain-containing protein	-
JJN14_RS05120 (JJN14_05120)	vicX	1051077..1051886 (-)	810	WP_201058013.1	MBL fold metallo-hydrolase	Regulator
JJN14_RS05125 (JJN14_05125)	micB	1051888..1053237 (-)	1350	WP_084863416.1	cell wall metabolism sensor histidine kinase VicK	Regulator
JJN14_RS05130 (JJN14_05130)	micA	1053230..1053937 (-)	708	WP_000722072.1	response regulator YycF	Regulator
JJN14_RS05135 (JJN14_05135)	mutY	1053992..1055167 (-)	1176	WP_201058014.1	A/G-specific adenine glycosylase	-
JJN14_RS05140 (JJN14_05140)	pta	1055250..1056224 (-)	975	WP_201058016.1	phosphate acetyltransferase	-
JJN14_RS05145 (JJN14_05145)	-	1056268..1057164 (-)	897	WP_201058018.1	RluA family pseudouridine synthase	-
JJN14_RS05150 (JJN14_05150)	-	1057161..1057979 (-)	819	WP_201058019.1	NAD kinase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51483.90 Da
• Isoelectric Point: 4.6866

>NTDB_id=526154 JJN14_RS05125 WP_084863416.1 1051888..1053237(-) (micB) [Streptococcus mitis strain S022-V7-A3]
MIELIRKNILTSDFIFILILLGFILIVTLLLLENRRDNIRLKQINQKVKDLIAGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGKITMINDMAKKQLGVQKEDVLNKSILELLEIEDEYELRDLITQVPE
LMIDSQDANGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMRGSDEEKKYELVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVTMKTTDDQMILSISDQGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide

• Length: 1350 bp

>NTDB_id=526154 JJN14_RS05125 WP_084863416.1 1051888..1053237(-) (micB) [Streptococcus mitis strain S022-V7-A3]
ATGATTGAATTGATTAGAAAAAACATTCTTACCAGTGATTTTATCTTTATTTTGATTTTATTGGGCTTTATCTTGATTGT
TACCTTACTCTTGCTAGAAAATCGTCGGGATAATATTCGGCTGAAGCAAATCAATCAAAAGGTAAAAGACCTGATTGCAG
GAGATTATTCTCAGGTGTTGGACATGCAGGGAAGCTCTGAAATCACTAATATTACCAATAATCTCAATGATTTATCAGAA
GTAATTCGTCTAACCCAGGAAAATCTGGAACAGGAGAGTAAAAGATTACATAGTATCCTGTCTTACATGACGGATGGAGT
CCTTGCGACCAATCGTCGTGGCAAGATTACTATGATTAATGACATGGCTAAGAAACAGCTAGGTGTTCAGAAAGAAGATG
TTCTAAACAAAAGTATCCTAGAATTGCTTGAGATTGAAGATGAGTATGAACTTCGTGATTTGATTACCCAAGTTCCTGAG
CTTATGATTGATTCTCAGGATGCCAATGGTGAATATCTGAGCCTTCGTGTACGTTTTGCCTTGGTTCGTCGAGAGTCTGG
CTTTATCTCAGGGTTGGTTGCAGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGGGAACGGAGGCTCTTTGTTT
CCAACGTTAGTCATGAGCTACGGACGCCTCTGACCAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGTGCCTTGTCA
GAACCTGTCGCTCCAGACTTTATCAAGGTGTCTCTAGACGAAACAAACCGTATGATGCGGATGGTGACGGATCTTCTCCA
TCTTTCACGTATTGATAATGCAACCAGTCATCTAGATGTGGAACTGATTAACTTTACAGCTTTTATTACTTTTATTCTTA
ACCGTTTTGATAAGATGAGGGGATCAGATGAAGAGAAGAAATACGAATTGGTTAGAGATTATCCGATCACGTCTGTCTGG
ATTGAAATTGATACAGACAAAATGACGCAGGTGATTGATAATATTCTTAACAATGCCATTAAGTATTCACCAGATGGTGG
GAAAATCACAGTGACCATGAAGACAACTGATGATCAGATGATTTTATCAATCTCAGACCAAGGCTTGGGTATTCCTAAGC
AGGATTTACCACGTATTTTTGACCGTTTCTACCGTGTTGACCGTGCTAGAAGTCGTGCTCAAGGTGGAACAGGTTTGGGA
CTGTCTATTGCTAAAGAAATTATCAAACAACATAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGTTCAACCTT
TACCATTGTACTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-198)

3D structure

• AlphaFold DB: A0A1X1KE01

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.977	97.773	0.88
vicK	Streptococcus mutans UA159	71.891	89.532	0.644