Detailed information NTG0052044

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: SMUGS5_RS07540
• Genome accession: NC_018089
• Coordinates: 1582416..1583030 (-)
• Length: 204 a.a.
• NCBI ID: WP_255264555.1
• Uniprot ID: -
• Organism: Streptococcus mutans GS-5
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1577416..1588030

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUGS5_RS07510 (SMUGS5_07520)	-	1577646..1578410 (-)	765	WP_002262678.1	ABC transporter ATP-binding protein	-
SMUGS5_RS07515 (SMUGS5_07525)	-	1578410..1579366 (-)	957	WP_002262677.1	branched-chain amino acid ABC transporter permease	-
SMUGS5_RS07520 (SMUGS5_07530)	-	1579370..1580239 (-)	870	WP_002262676.1	branched-chain amino acid ABC transporter permease	-
SMUGS5_RS07525 (SMUGS5_07535)	-	1580323..1581495 (-)	1173	WP_002264030.1	ABC transporter substrate-binding protein	-
SMUGS5_RS07530 (SMUGS5_07540)	-	1581598..1581846 (-)	249	WP_002262674.1	YlbG family protein	-
SMUGS5_RS07535 (SMUGS5_07545)	-	1581853..1582293 (-)	441	WP_002270498.1	YlbF family regulator	-
SMUGS5_RS07540 (SMUGS5_07550)	clpP	1582416..1583030 (-)	615	WP_255264555.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
SMUGS5_RS07545 (SMUGS5_07555)	upp	1583340..1583969 (-)	630	WP_002262598.1	uracil phosphoribosyltransferase	-
SMUGS5_RS07550 (SMUGS5_07560)	-	1584282..1585445 (-)	1164	WP_002280647.1	MalY/PatB family protein	-
SMUGS5_RS07555	-	1585460..1586553 (-)	1094	Protein_1484	cystathionine gamma-synthase	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 22651.08 Da
• Isoelectric Point: 5.3673

>NTDB_id=52044 SMUGS5_RS07540 WP_255264555.1 1582416..1583030(-) (clpP) [Streptococcus mutans GS-5]
MELKEKYSMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINSPGGSVSAG
LAIVDTMNFIKSDVQTIVMGIAASMGTIVASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQSDMAIAAEQLLKTRKKLEK
ILSDNSGKTVKQIHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide

• Length: 615 bp

>NTDB_id=52044 SMUGS5_RS07540 WP_255264555.1 1582416..1583030(-) (clpP) [Streptococcus mutans GS-5]
ATTGAATTAAAGGAGAAATACAGTATGATTCCTGTAGTTATTGAACAAACGAGCCGTGGTGAACGCTCTTATGATATTTA
TTCACGTCTATTAAAAGATCGTATTATTATGTTGACTGGTCCTGTTGAAGACAATATGGCAAATTCCATTATTGCTCAGT
TACTGTTTCTTGATGCACAAGATAATACCAAAGACATTTATCTTTATATTAATTCACCGGGTGGTTCTGTTTCAGCTGGT
CTTGCTATTGTTGATACGATGAACTTTATTAAGTCTGATGTTCAAACGATTGTTATGGGTATTGCTGCTTCCATGGGAAC
AATCGTCGCTTCTAGCGGTGCCAAAGGAAAACGTTTTATGTTACCAAATGCAGAATATCTTATCCATCAGCCAATGGGCG
GTACAGGCGGTGGCACACAGCAGTCTGATATGGCTATTGCTGCCGAACAATTGCTTAAAACACGCAAAAAATTAGAAAAG
ATTCTATCGGATAATTCTGGAAAAACAGTAAAACAAATTCATAAGGATGCTGAACGTGATTATTGGATGGATGCTAAGGA
AACATTAAAGTATGGCTTCATCGATGAAATCATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (19-200)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	99.02	100	0.99
clpP	Streptococcus pyogenes JRS4	89.796	96.078	0.863
clpP	Streptococcus pyogenes MGAS315	89.796	96.078	0.863
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.245	96.078	0.838
clpP	Streptococcus thermophilus LMD-9	86.735	96.078	0.833
clpP	Lactococcus lactis subsp. cremoris KW2	86.735	96.078	0.833
clpP	Streptococcus thermophilus LMG 18311	86.735	96.078	0.833
clpP	Streptococcus pneumoniae Rx1	85.641	95.588	0.819
clpP	Streptococcus pneumoniae D39	85.641	95.588	0.819
clpP	Streptococcus pneumoniae R6	85.641	95.588	0.819
clpP	Streptococcus pneumoniae TIGR4	85.641	95.588	0.819
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	94.608	0.544
clpP	Bacillus subtilis subsp. subtilis str. 168	55.838	96.569	0.539