Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SMUGS5_RS06825 Genome accession   NC_018089
Coordinates   1448550..1449257 (-) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1443550..1454257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS06810 (SMUGS5_06815) rnc 1445603..1446298 (-) 696 WP_002266141.1 ribonuclease III -
  SMUGS5_RS06815 (SMUGS5_06820) vicX 1446405..1447208 (-) 804 WP_002262928.1 MBL fold metallo-hydrolase Regulator
  SMUGS5_RS06820 (SMUGS5_06825) vicK 1447205..1448557 (-) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SMUGS5_RS06825 (SMUGS5_06830) vicR 1448550..1449257 (-) 708 WP_002262930.1 response regulator YycF Regulator
  SMUGS5_RS06830 (SMUGS5_06835) - 1449610..1450392 (+) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  SMUGS5_RS06835 (SMUGS5_06840) - 1450389..1451201 (+) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  SMUGS5_RS06840 (SMUGS5_06845) - 1451219..1451923 (+) 705 WP_002279779.1 amino acid ABC transporter permease -
  SMUGS5_RS06845 (SMUGS5_06850) - 1451938..1452588 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  SMUGS5_RS06850 (SMUGS5_06855) endA 1452656..1453537 (-) 882 WP_002279778.1 DNA/RNA non-specific endonuclease Machinery gene
  SMUGS5_RS06855 (SMUGS5_06860) - 1453579..1453767 (-) 189 WP_002264826.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=52040 SMUGS5_RS06825 WP_002262930.1 1448550..1449257(-) (vicR) [Streptococcus mutans GS-5]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=52040 SMUGS5_RS06825 WP_002262930.1 1448550..1449257(-) (vicR) [Streptococcus mutans GS-5]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGACTTGATTATATTGGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTTAGAAAAAACAGCCATGTTCCAATTATTATGTTATCAGCT
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGTGCTGATGATTATGTGACTAAACCTTTTTCTAATCGTGA
ATTACTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCCGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATCTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAGTTA
ACTCACCGTGAGTTTGAGCTGTTGCATCACTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTTACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTATTACATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451

Multiple sequence alignment