Detailed information NTG0052041

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: SMUGS5_RS06850
• Genome accession: NC_018089
• Coordinates: 1452656..1453537 (-)
• Length: 293 a.a.
• NCBI ID: WP_002279778.1
• Uniprot ID: -
• Organism: Streptococcus mutans GS-5
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1447656..1458537

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUGS5_RS06825 (SMUGS5_06830)	vicR	1448550..1449257 (-)	708	WP_002262930.1	response regulator YycF	Regulator
SMUGS5_RS06830 (SMUGS5_06835)	-	1449610..1450392 (+)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
SMUGS5_RS06835 (SMUGS5_06840)	-	1450389..1451201 (+)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
SMUGS5_RS06840 (SMUGS5_06845)	-	1451219..1451923 (+)	705	WP_002279779.1	amino acid ABC transporter permease	-
SMUGS5_RS06845 (SMUGS5_06850)	-	1451938..1452588 (+)	651	WP_002262934.1	amino acid ABC transporter permease	-
SMUGS5_RS06850 (SMUGS5_06855)	endA	1452656..1453537 (-)	882	WP_002279778.1	DNA/RNA non-specific endonuclease	Machinery gene
SMUGS5_RS06855 (SMUGS5_06860)	-	1453579..1453767 (-)	189	WP_002264826.1	DNA-directed RNA polymerase subunit beta	-
SMUGS5_RS06860 (SMUGS5_06865)	murA	1453770..1455041 (-)	1272	WP_002273074.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SMUGS5_RS06865 (SMUGS5_06870)	-	1455107..1455340 (-)	234	WP_002285829.1	DUF1146 family protein	-
SMUGS5_RS06870 (SMUGS5_06875)	-	1455612..1456028 (-)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
SMUGS5_RS06875 (SMUGS5_06880)	atpD	1456042..1457448 (-)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
SMUGS5_RS06880 (SMUGS5_06885)	-	1457474..1458352 (-)	879	WP_002279777.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32184.77 Da
• Isoelectric Point: 9.5337

>NTDB_id=52041 SMUGS5_RS06850 WP_002279778.1 1452656..1453537(-) (endA) [Streptococcus mutans GS-5]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYANNQTKIVQGQTVPTVANALLNKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=52041 SMUGS5_RS06850 WP_002279778.1 1452656..1453537(-) (endA) [Streptococcus mutans GS-5]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAGTTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAATAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAATAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (103-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	63.675	79.863	0.509
endA	Streptococcus pneumoniae D39	63.675	79.863	0.509
endA	Streptococcus pneumoniae R6	63.675	79.863	0.509
endA	Streptococcus pneumoniae TIGR4	63.675	79.863	0.509