Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SMUGS5_RS06820 Genome accession   NC_018089
Coordinates   1447205..1448557 (-) Length   450 a.a.
NCBI ID   WP_002264821.1    Uniprot ID   A0AAX1K2Z0
Organism   Streptococcus mutans GS-5     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1442205..1453557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS06810 (SMUGS5_06815) rnc 1445603..1446298 (-) 696 WP_002266141.1 ribonuclease III -
  SMUGS5_RS06815 (SMUGS5_06820) vicX 1446405..1447208 (-) 804 WP_002262928.1 MBL fold metallo-hydrolase Regulator
  SMUGS5_RS06820 (SMUGS5_06825) vicK 1447205..1448557 (-) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SMUGS5_RS06825 (SMUGS5_06830) vicR 1448550..1449257 (-) 708 WP_002262930.1 response regulator YycF Regulator
  SMUGS5_RS06830 (SMUGS5_06835) - 1449610..1450392 (+) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  SMUGS5_RS06835 (SMUGS5_06840) - 1450389..1451201 (+) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  SMUGS5_RS06840 (SMUGS5_06845) - 1451219..1451923 (+) 705 WP_002279779.1 amino acid ABC transporter permease -
  SMUGS5_RS06845 (SMUGS5_06850) - 1451938..1452588 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  SMUGS5_RS06850 (SMUGS5_06855) endA 1452656..1453537 (-) 882 WP_002279778.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51752.41 Da        Isoelectric Point: 4.4951

>NTDB_id=52039 SMUGS5_RS06820 WP_002264821.1 1447205..1448557(-) (vicK) [Streptococcus mutans GS-5]
MTNVFESSPLFLRILLAVLIILLFFYFIFLNYREYKNNNQVKQLNAKVRSLITGHYTDKLKVEDNSDLSELVNNVNDLSE
VFRLTHENLAQEKNRLTSILSYMTDGVLATDRRGKITVINDMAQKQLNVTREQALECNILDILDDDSYTYNDLITKTPEI
VLTRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSHLDVELTNFTAFMNYILDRFDQIQSQQSTNKVYEIIRDYPDKSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKVTVTMQTTDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWANSEEGEGSTFTIVLPYENDNDAIDEWEEDEDES

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=52039 SMUGS5_RS06820 WP_002264821.1 1447205..1448557(-) (vicK) [Streptococcus mutans GS-5]
ATGACTAATGTGTTTGAATCAAGTCCCTTATTTTTACGAATTTTATTAGCAGTTTTAATCATTTTACTCTTTTTTTATTT
TATTTTTCTCAATTACAGAGAGTATAAAAATAATAATCAAGTTAAACAGTTAAATGCTAAAGTACGTTCTTTGATTACTG
GCCATTATACTGATAAATTAAAGGTTGAGGATAACTCTGACTTGTCAGAACTAGTGAATAACGTTAATGATTTATCAGAA
GTTTTCCGTTTAACGCATGAAAATTTGGCACAGGAGAAAAACCGTCTGACTAGTATTTTATCTTATATGACAGATGGTGT
TTTGGCAACAGATCGCCGCGGAAAGATTACCGTTATTAATGATATGGCGCAAAAGCAACTGAATGTAACGCGTGAGCAGG
CATTGGAGTGCAATATTCTGGATATTTTGGATGATGATAGTTATACTTACAATGATTTGATTACAAAAACGCCAGAAATT
GTTCTGACGCGGCGTGATGAATATGATGAATTTATCACTTTACGCATTCGTTTTGCCTTAAACCGCCGTGAAAGTGGCTT
TATTTCAGGACTAATTGCTGTCTTGCATGATGCGACCGAACAGGAAAAAGAAGAACGTGAACGCCGTCTCTTTGTTTCTA
ATGTCAGTCATGAACTGCGGACACCATTAACCTCTGTAAAGTCCTATTTAGAAGCTTTGGACGATGGTGCCCTGACAGAA
TCAGTGGCTCCTAGTTTTATCAAGGTATCACTTGATGAGACTAATCGCATGATGCGTATGATTACTGATTTACTTAGCTT
ATCACGTATTGATAATCAGACCAGTCATTTAGATGTTGAATTGACGAATTTTACAGCTTTTATGAATTATATTCTGGATC
GCTTTGATCAAATTCAAAGTCAGCAATCAACTAATAAGGTTTACGAAATTATTAGAGATTATCCTGACAAATCAGTTTGG
ATTGAAATTGATACCGATAAAATGACTCAGGTAATTGATAATATTTTAAATAATGCAATCAAATATTCACCTGATGGCGG
TAAGGTGACTGTAACGATGCAAACAACAGATACCCAACTCATCCTTTCTATATCCGACCAAGGCTTGGGTATTCCTAAGA
AGGATCTCCCTCTTATTTTTGACCGTTTTTATCGTGTTGATAAGGCAAGAAGCCGTGCTCAAGGTGGGACTGGTTTAGGA
TTAGCAATCGCCAAAGAAATTGTCAAACAGCATAAAGGCTTTATTTGGGCCAATAGTGAGGAAGGCGAAGGGTCGACCTT
TACCATCGTTTTACCTTATGAAAATGATAATGATGCAATTGATGAATGGGAAGAAGATGAAGACGAATCATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

99.556

100

0.996
  micB Streptococcus pneumoniae Cp1015

67.599

95.333

0.644

Multiple sequence alignment