Detailed information NTG0519116

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: IGS65_RS03225
• Genome accession: NZ_CP066294
• Coordinates: 645287..646129 (-)
• Length: 280 a.a.
• NCBI ID: WP_002303890.1
• Uniprot ID: A0AAX1K4S9
• Organism: Streptococcus mutans strain 27-3
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 640287..651129

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGS65_RS03215 (IGS65_003215)	trmFO	641375..642709 (-)	1335	WP_192072209.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
IGS65_RS03220 (IGS65_003220)	topA	643076..645193 (-)	2118	WP_002282653.1	type I DNA topoisomerase	-
IGS65_RS03225 (IGS65_003225)	dprA	645287..646129 (-)	843	WP_002303890.1	DNA-processing protein DprA	Machinery gene
IGS65_RS03230 (IGS65_003230)	-	646296..646577 (-)	282	WP_002262863.1	hypothetical protein	-
IGS65_RS03235 (IGS65_003235)	-	646649..647665 (-)	1017	WP_002265840.1	siderophore ABC transporter substrate-binding protein	-
IGS65_RS03240 (IGS65_003240)	-	647758..648519 (-)	762	WP_192072208.1	ATP-binding cassette domain-containing protein	-
IGS65_RS03245 (IGS65_003245)	-	648516..649487 (-)	972	WP_192072207.1	iron chelate uptake ABC transporter family permease subunit	-
IGS65_RS03250 (IGS65_003250)	-	649484..650446 (-)	963	WP_002270387.1	iron chelate uptake ABC transporter family permease subunit	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31346.30 Da
• Isoelectric Point: 9.1954

>NTDB_id=519116 IGS65_RS03225 WP_002303890.1 645287..646129(-) (dprA) [Streptococcus mutans strain 27-3]
MDNFQLFKLKKAGLTNLNILNIIDYEERTQKSLSLRDMAVVSKNKKPLIFMEHYKNLDSKALRKEFNRFPSLSILDKEYP
LELKNIYNPPVLLFYQGDLDLLARPKLAVVGSRNASQMGVAAVKKIIQDLSKQFVIISGLARGIDTAAHLASLKSGGATI
AVIGTGLDIHYPKENRRLQDYIAKNHLLLSEYEAQSQPLKYHFPERNRIIAGLSQGVMVAEAKIRSGSLITCERAMEEGR
DVFVVPGNILDGQSEGCHHLIQEGAKCITSGFDILNEFNF

Nucleotide

• Length: 843 bp

>NTDB_id=519116 IGS65_RS03225 WP_002303890.1 645287..646129(-) (dprA) [Streptococcus mutans strain 27-3]
ATGGATAATTTTCAACTATTTAAACTTAAAAAAGCTGGTCTAACAAATCTGAATATCTTAAATATTATTGATTATGAAGA
GAGGACACAAAAATCCTTGTCTCTTCGTGATATGGCTGTTGTTTCCAAAAATAAAAAGCCTTTAATTTTTATGGAACATT
ACAAGAATCTTGATAGCAAAGCATTACGCAAAGAATTTAATCGTTTTCCTTCTTTATCCATTTTGGACAAAGAATATCCC
TTGGAACTTAAAAATATTTATAATCCGCCTGTTCTTCTATTTTATCAGGGAGACTTAGACTTGCTAGCTCGGCCTAAATT
AGCAGTAGTTGGTTCTCGCAACGCCAGTCAAATGGGAGTAGCTGCTGTTAAAAAGATCATACAAGACTTAAGTAAGCAAT
TTGTTATTATTAGCGGTTTAGCGCGTGGTATTGATACTGCAGCACATTTAGCAAGTCTTAAAAGCGGTGGAGCAACAATT
GCGGTCATCGGTACTGGACTAGATATTCATTATCCTAAAGAAAATCGAAGACTGCAGGATTATATTGCAAAGAATCATTT
GCTCTTATCAGAATATGAAGCACAGAGTCAACCTCTTAAGTATCATTTTCCTGAGCGGAACCGCATTATTGCTGGGTTAT
CTCAAGGTGTTATGGTAGCAGAAGCAAAAATTCGTTCGGGTAGTCTGATTACTTGTGAACGTGCTATGGAAGAAGGACGC
GATGTTTTTGTTGTACCAGGAAATATTTTAGACGGCCAGTCAGAAGGATGCCATCACCTGATTCAAGAAGGAGCAAAATG
CATTACATCAGGCTTTGATATTTTAAATGAGTTTAACTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	99.643	100	0.996
dprA/cilB/dalA	Streptococcus mitis SK321	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.857	100	0.629
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.5	100	0.625
dprA	Lactococcus lactis subsp. cremoris KW2	58.633	99.286	0.582
dprA	Legionella pneumophila strain ERS1305867	44.77	85.357	0.382
dprA	Staphylococcus aureus N315	38.258	94.286	0.361