Detailed information NTG0519103

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: IGS65_RS00405
• Genome accession: NZ_CP066294
• Coordinates: 67271..67885 (+)
• Length: 204 a.a.
• NCBI ID: WP_280517818.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain 27-3
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 62271..72885

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGS65_RS00390 (IGS65_000390)	-	63798..64892 (+)	1095	WP_192072355.1	cystathionine gamma-synthase	-
IGS65_RS00395 (IGS65_000395)	-	64907..66070 (+)	1164	WP_002285023.1	MalY/PatB family protein	-
IGS65_RS00400 (IGS65_000400)	upp	66383..67012 (+)	630	WP_002262598.1	uracil phosphoribosyltransferase	-
IGS65_RS00405 (IGS65_000405)	clpP	67271..67885 (+)	615	WP_280517818.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
IGS65_RS00410 (IGS65_000410)	-	68001..68441 (+)	441	WP_002275751.1	YlbF family regulator	-
IGS65_RS00415 (IGS65_000415)	-	68448..68696 (+)	249	WP_002262674.1	YlbG family protein	-
IGS65_RS00420 (IGS65_000420)	-	68799..69971 (+)	1173	WP_002271436.1	ABC transporter substrate-binding protein	-
IGS65_RS00425 (IGS65_000425)	-	70055..70924 (+)	870	WP_002262676.1	branched-chain amino acid ABC transporter permease	-
IGS65_RS00430 (IGS65_000430)	-	70928..71884 (+)	957	WP_002291392.1	branched-chain amino acid ABC transporter permease	-
IGS65_RS00435 (IGS65_000435)	-	71884..72648 (+)	765	WP_002262678.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 22681.15 Da
• Isoelectric Point: 5.3673

>NTDB_id=519103 IGS65_RS00405 WP_280517818.1 67271..67885(+) (clpP) [Streptococcus mutans strain 27-3]
MELKEKYSMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGLVEDNMANSIIAQLLFLDAQDNTKDIYLYINSPGGSVSAG
LAIVDTMNFIKSDVQTIVMGIAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQSDMAIAAEQLLKTRKKLEK
ILSDNSGKTVKQIHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide

• Length: 615 bp

>NTDB_id=519103 IGS65_RS00405 WP_280517818.1 67271..67885(+) (clpP) [Streptococcus mutans strain 27-3]
ATTGAATTAAAGGAGAAATACAGTATGATTCCTGTAGTTATTGAACAAACGAGCCGTGGTGAACGCTCTTATGATATTTA
TTCACGTCTATTAAAAGATCGTATTATTATGTTGACTGGTCTTGTTGAAGACAATATGGCAAATTCCATTATTGCTCAGT
TACTGTTTCTTGATGCACAAGATAATACCAAAGACATTTATCTTTATATTAATTCACCTGGTGGTTCTGTTTCAGCTGGT
CTTGCTATTGTTGATACGATGAACTTTATTAAGTCTGATGTTCAAACGATTGTTATGGGTATTGCTGCTTCCATGGGAAC
AATCATCGCTTCTAGCGGTGCCAAAGGAAAACGTTTTATGTTACCAAATGCAGAATATCTTATCCATCAGCCAATGGGCG
GTACAGGCGGTGGCACACAGCAGTCTGATATGGCTATTGCTGCCGAACAATTGCTTAAAACACGCAAAAAATTAGAAAAG
ATTCTATCGGATAATTCTGGAAAAACAGTAAAACAAATTCATAAGGATGCTGAACGTGATTATTGGATGGATGCTAAGGA
AACATTAAAGTATGGCTTCATCGATGAAATCATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (19-200)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	99.02	100	0.99
clpP	Streptococcus pyogenes JRS4	89.796	96.078	0.863
clpP	Streptococcus pyogenes MGAS315	89.796	96.078	0.863
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.245	96.078	0.838
clpP	Streptococcus thermophilus LMD-9	86.735	96.078	0.833
clpP	Lactococcus lactis subsp. cremoris KW2	86.735	96.078	0.833
clpP	Streptococcus thermophilus LMG 18311	86.735	96.078	0.833
clpP	Streptococcus pneumoniae Rx1	85.641	95.588	0.819
clpP	Streptococcus pneumoniae D39	85.641	95.588	0.819
clpP	Streptococcus pneumoniae R6	85.641	95.588	0.819
clpP	Streptococcus pneumoniae TIGR4	85.641	95.588	0.819
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	94.608	0.544
clpP	Bacillus subtilis subsp. subtilis str. 168	55.838	96.569	0.539