Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   JC776_RS09845 Genome accession   NZ_CP066194
Coordinates   1971599..1972180 (-) Length   193 a.a.
NCBI ID   WP_012096148.1    Uniprot ID   A7GUT3
Organism   Bacillus cytotoxicus strain E8.1     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1971599..1983582 1971599..1972180 within 0


Gene organization within MGE regions


Location: 1971599..1983582
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JC776_RS09845 (JC776_09845) clpP 1971599..1972180 (-) 582 WP_012096148.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  JC776_RS09850 (JC776_09850) - 1972423..1973292 (-) 870 WP_087095558.1 DUF421 domain-containing protein -
  JC776_RS09855 (JC776_09855) - 1973313..1973519 (-) 207 WP_012096145.1 DUF1657 domain-containing protein -
  JC776_RS09860 (JC776_09860) spoVAE 1973531..1973881 (-) 351 WP_012096144.1 stage V sporulation protein AE -
  JC776_RS09865 (JC776_09865) spoVAD 1973878..1974894 (-) 1017 WP_012096143.1 stage V sporulation protein AD -
  JC776_RS09870 (JC776_09870) spoVAC 1974895..1975371 (-) 477 WP_012096142.1 stage V sporulation protein AC -
  JC776_RS09875 (JC776_09875) - 1975406..1975894 (-) 489 WP_012096141.1 YhcN/YlaJ family sporulation lipoprotein -
  JC776_RS09880 (JC776_09880) - 1975985..1976191 (-) 207 WP_012096140.1 DUF1657 domain-containing protein -
  JC776_RS22075 - 1976880..1977173 (+) 294 WP_246862599.1 phage integrase N-terminal SAM-like domain-containing protein -
  JC776_RS22080 - 1977246..1977605 (+) 360 WP_239430993.1 site-specific integrase -
  JC776_RS09895 (JC776_09895) - 1977764..1977952 (-) 189 WP_087095557.1 Phr family secreted Rap phosphatase inhibitor -
  JC776_RS09900 (JC776_09900) - 1977952..1978986 (-) 1035 WP_239430992.1 tetratricopeptide repeat protein -
  JC776_RS09905 (JC776_09905) - 1979198..1980217 (+) 1020 Protein_1886 T7SS effector LXG polymorphic toxin -
  JC776_RS22085 - 1980241..1980342 (+) 102 Protein_1887 GntR family transcriptional regulator -
  JC776_RS09910 (JC776_09910) rpoN 1980857..1982164 (+) 1308 WP_087095556.1 RNA polymerase factor sigma-54 -
  JC776_RS09915 (JC776_09915) - 1982174..1982419 (+) 246 WP_012096138.1 glutaredoxin family protein -
  JC776_RS09920 (JC776_09920) cggR 1982554..1983582 (+) 1029 WP_012096137.1 gapA transcriptional regulator CggR -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21418.68 Da        Isoelectric Point: 5.0645

>NTDB_id=518397 JC776_RS09845 WP_012096148.1 1971599..1972180(-) (clpP) [Bacillus cytotoxicus strain E8.1]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHLYINSPGGSITAGMAIYDT
MQFIKPNVSTICIGMAASMGAFLLAAGEKGKRFALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLRDKLNKILAERTGQ
PLEVIERDTDRDNFMTAEKALEYGLIDRIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=518397 JC776_RS09845 WP_012096148.1 1971599..1972180(-) (clpP) [Bacillus cytotoxicus strain E8.1]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGCGCAATTGATGACAATGTAGCAAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCATTTATACATTAACAGCCCTGGTGGTTCTATTACAGCAGGTATGGCCATCTATGACACA
ATGCAGTTCATTAAGCCAAACGTATCAACTATTTGTATCGGTATGGCAGCATCTATGGGTGCATTCCTACTTGCAGCTGG
TGAAAAAGGAAAACGCTTCGCACTTCCAAACAGTGAAGTTATGATCCACCAACCACTTGGTGGTGCACAAGGACAAGCAA
CTGAAATTGAAATCGCTGCAAAACGCATCCTATTCCTACGCGATAAATTAAACAAAATCCTTGCAGAACGCACAGGCCAA
CCACTAGAAGTCATCGAACGCGACACAGACCGTGACAACTTCATGACAGCCGAAAAAGCACTAGAATACGGCCTAATCGA
TAGAATCTTTACAAACCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7GUT3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

92.188

99.482

0.917
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.085

97.409

0.663
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Streptococcus pneumoniae TIGR4

59.375

99.482

0.591
  clpP Streptococcus pneumoniae D39

59.375

99.482

0.591
  clpP Lactococcus lactis subsp. cremoris KW2

59.375

99.482

0.591
  clpP Streptococcus pneumoniae Rx1

59.375

99.482

0.591
  clpP Streptococcus pneumoniae R6

59.375

99.482

0.591
  clpP Streptococcus pyogenes JRS4

57.812

99.482

0.575
  clpP Streptococcus pyogenes MGAS315

57.812

99.482

0.575
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

57.292

99.482

0.57
  clpP Streptococcus mutans UA159

56.995

100

0.57