Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   JDY60_RS03135 Genome accession   NZ_CP066172
Coordinates   657648..658355 (+) Length   235 a.a.
NCBI ID   WP_200371373.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 652648..663355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS03110 (JDY60_03110) - 652946..653617 (+) 672 WP_000151555.1 GTP pyrophosphokinase family protein -
  JDY60_RS03115 (JDY60_03115) - 653601..654419 (+) 819 WP_200371367.1 NAD kinase -
  JDY60_RS03120 (JDY60_03120) - 654416..655312 (+) 897 WP_200371369.1 RluA family pseudouridine synthase -
  JDY60_RS03125 (JDY60_03125) pta 655356..656330 (+) 975 WP_084859882.1 phosphate acetyltransferase -
  JDY60_RS03130 (JDY60_03130) mutY 656413..657591 (+) 1179 WP_200371371.1 A/G-specific adenine glycosylase -
  JDY60_RS03135 (JDY60_03135) micA 657648..658355 (+) 708 WP_200371373.1 response regulator YycF Regulator
  JDY60_RS03140 (JDY60_03140) micB 658348..659697 (+) 1350 WP_200371375.1 cell wall metabolism sensor histidine kinase VicK Regulator
  JDY60_RS03145 (JDY60_03145) vicX 659699..660508 (+) 810 WP_200371377.1 MBL fold metallo-hydrolase Regulator
  JDY60_RS03150 (JDY60_03150) - 660648..661943 (+) 1296 WP_200371379.1 AAA family ATPase -
  JDY60_RS03155 (JDY60_03155) - 661940..662563 (+) 624 WP_200371381.1 retron system putative HNH endonuclease -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27061.92 Da        Isoelectric Point: 4.6177

>NTDB_id=518040 JDY60_RS03135 WP_200371373.1 657648..658355(+) (micA) [Streptococcus oralis strain SF100]
MKKILIVDDEKPISDIIKFNMVKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKRTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=518040 JDY60_RS03135 WP_200371373.1 657648..658355(+) (micA) [Streptococcus oralis strain SF100]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGTCAAGGAAGGTTATGA
AGTTGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGTTATTTGAAGCCGAGCAACCCGACATTATTATCCTAGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTAGCCAAAGCCATTCGCAAGACCAGTAGTGTTCCTATCATTATGCTGTCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTGGAACTAGGGGCAGATGATTATGTCACAAAGCCCTTCTCAAATCGTGA
GTTGCAGGCGCGTGTCAAGGCTTTACTTCGCCGTACCGACTTGGTTTCAGTTGATAGTCAAGAGTCTGATGAGAAGAGGA
CGCAGCCCTTACAAATTGGTGATTTGGAAATCGTTCCAGATGCTTATGTGGCTAAGAAATATGGTGAGGAATTAGATTTG
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCATCTCATATTGGACAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTTTGGGGTTATGATTATTTTGGTGATGTTCGTACAGTGGACGTGACCATTAGACGTTTGCGTGAAAAAATTGAAGATA
CTCCAAGCCGTCCAGAGTATATCCTCACCCGTCGTGGTGTTGGCTACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.021

100

0.77
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.723

98.298

0.43
  covR Streptococcus salivarius strain HSISS4

43.723

98.298

0.43
  scnR Streptococcus mutans UA159

37.179

99.574

0.37