Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   JDY60_RS03140 Genome accession   NZ_CP066172
Coordinates   658348..659697 (+) Length   449 a.a.
NCBI ID   WP_200371375.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 653348..664697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS03115 (JDY60_03115) - 653601..654419 (+) 819 WP_200371367.1 NAD kinase -
  JDY60_RS03120 (JDY60_03120) - 654416..655312 (+) 897 WP_200371369.1 RluA family pseudouridine synthase -
  JDY60_RS03125 (JDY60_03125) pta 655356..656330 (+) 975 WP_084859882.1 phosphate acetyltransferase -
  JDY60_RS03130 (JDY60_03130) mutY 656413..657591 (+) 1179 WP_200371371.1 A/G-specific adenine glycosylase -
  JDY60_RS03135 (JDY60_03135) micA 657648..658355 (+) 708 WP_200371373.1 response regulator YycF Regulator
  JDY60_RS03140 (JDY60_03140) micB 658348..659697 (+) 1350 WP_200371375.1 cell wall metabolism sensor histidine kinase VicK Regulator
  JDY60_RS03145 (JDY60_03145) vicX 659699..660508 (+) 810 WP_200371377.1 MBL fold metallo-hydrolase Regulator
  JDY60_RS03150 (JDY60_03150) - 660648..661943 (+) 1296 WP_200371379.1 AAA family ATPase -
  JDY60_RS03155 (JDY60_03155) - 661940..662563 (+) 624 WP_200371381.1 retron system putative HNH endonuclease -
  JDY60_RS03160 (JDY60_03160) - 662729..663958 (-) 1230 WP_200371383.1 transposase -
  JDY60_RS03165 (JDY60_03165) - 664043..664390 (-) 348 WP_200371385.1 thioredoxin -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51563.90 Da        Isoelectric Point: 4.5770

>NTDB_id=518041 JDY60_RS03140 WP_200371375.1 658348..659697(+) (micB) [Streptococcus oralis strain SF100]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNISNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=518041 JDY60_RS03140 WP_200371375.1 658348..659697(+) (micB) [Streptococcus oralis strain SF100]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGTGATTTTATCTTTATCTTGATTTTACTTGGCTTTATCTTGGTGGT
AACCTTGCTCTTACTAGAAAATCGTCGAGATAATATCCGTCTGAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTACAAGGCAGTACAGAAATCACCAATATTAGCAATAATCTGAACGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACCAATCGCCGTGGCCAGATTACTATGATCAACGATATGGCCAAGAAACAGCTCGGTGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTCGAATTGCTTAAGATAGAAGATGAGTATGAGTTGCGTGACCTGATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTGAATGGTGAATATCTAAGCCTTCGTGTACGTTTTGCTCTGGTTCGCCGTGAGTCAGG
TTTTATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAACAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CTAACGTGAGTCACGAGTTGCGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGAGCCCTGTAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGTATGGTGACAGATCTCTTACA
TCTCTCTCGTATTGATAATGCGACAAGTCAGCTAGATGTGGAATTGATTAATTTTACAGCATTCATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGTCAGGATGACGAGAAAAAATATGAGCTTGTCAGAGATTACCCTATTAATTCAGTTTGG
ATCGAGATTGATACCGATAAGATGACTCAGGTGATTGATAATATTCTTAACAATGCCATTAAGTACTCACCAGATGGTGG
GAAAATCACTGTCAGCATGAAAACTACTGATGACCAGATGATTTTATCCATCAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCGAAGATTTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCCCAAGGTGGAACTGGTCTAGGT
CTGGCCATCGCTAAAGAAATCATCAAACAACACAATGGTTTTATATGGGCCAAAAGTGAATACGGTAAGGGATCGACCTT
TACCATCGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.294

97.773

0.873
  vicK Streptococcus mutans UA159

70.896

89.532

0.635