Detailed information NTG0517359

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: I6I02_RS04870
• Genome accession: NZ_CP066093
• Coordinates: 1102479..1103186 (-)
• Length: 235 a.a.
• NCBI ID: WP_037600497.1
• Uniprot ID: A0AAW7PG55
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1097479..1108186

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS04845 (I6I02_04845)	yidA	1097832..1098641 (+)	810	WP_002890845.1	sugar-phosphatase	-
I6I02_RS04850 (I6I02_04850)	-	1098643..1099857 (+)	1215	WP_155198602.1	aminoacyltransferase	-
I6I02_RS04855 (I6I02_04855)	-	1099909..1100268 (-)	360	WP_037597735.1	YbaN family protein	-
I6I02_RS04860 (I6I02_04860)	vicX	1100328..1101140 (-)	813	WP_037600654.1	MBL fold metallo-hydrolase	Regulator
I6I02_RS04865 (I6I02_04865)	vicK	1101146..1102486 (-)	1341	WP_198463940.1	cell wall metabolism sensor histidine kinase VicK	Regulator
I6I02_RS04870 (I6I02_04870)	vicR	1102479..1103186 (-)	708	WP_037600497.1	response regulator YycF	Regulator
I6I02_RS04875 (I6I02_04875)	-	1103472..1104239 (+)	768	WP_002885036.1	amino acid ABC transporter ATP-binding protein	-
I6I02_RS04880 (I6I02_04880)	-	1104249..1105082 (+)	834	WP_198463941.1	transporter substrate-binding domain-containing protein	-
I6I02_RS04885 (I6I02_04885)	-	1105100..1105798 (+)	699	WP_198463942.1	amino acid ABC transporter permease	-
I6I02_RS04890 (I6I02_04890)	-	1105810..1106460 (+)	651	WP_037601175.1	amino acid ABC transporter permease	-
I6I02_RS04895 (I6I02_04895)	-	1106651..1107418 (+)	768	WP_048675082.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27072.92 Da
• Isoelectric Point: 4.8387

>NTDB_id=517359 I6I02_RS04870 WP_037600497.1 1102479..1103186(-) (vicR) [Streptococcus salivarius strain FDAARGOS_1045]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTNHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=517359 I6I02_RS04870 WP_037600497.1 1102479..1103186(-) (vicR) [Streptococcus salivarius strain FDAARGOS_1045]
ATGAAAAAAATTCTTGTTGTTGATGATGAAAGACCAATTTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGTCGTGAAGCATTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGCTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAATCATACACCAATTATCATGCTTTCAGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCAGATGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCAGGCA
AGCAGGAAATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAACTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTAATGACGCGTGAACATTTGCTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGACA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.106	100	0.851
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.136	100	0.383