Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I6I02_RS04865 Genome accession   NZ_CP066093
Coordinates   1101146..1102486 (-) Length   446 a.a.
NCBI ID   WP_198463940.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1096146..1107486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS04835 (I6I02_04835) - 1096317..1096703 (-) 387 WP_049545096.1 DUF1934 domain-containing protein -
  I6I02_RS04840 (I6I02_04840) - 1096796..1097653 (-) 858 WP_198463939.1 GNAT family N-acetyltransferase -
  I6I02_RS04845 (I6I02_04845) yidA 1097832..1098641 (+) 810 WP_002890845.1 sugar-phosphatase -
  I6I02_RS04850 (I6I02_04850) - 1098643..1099857 (+) 1215 WP_155198602.1 aminoacyltransferase -
  I6I02_RS04855 (I6I02_04855) - 1099909..1100268 (-) 360 WP_037597735.1 YbaN family protein -
  I6I02_RS04860 (I6I02_04860) vicX 1100328..1101140 (-) 813 WP_037600654.1 MBL fold metallo-hydrolase Regulator
  I6I02_RS04865 (I6I02_04865) vicK 1101146..1102486 (-) 1341 WP_198463940.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6I02_RS04870 (I6I02_04870) vicR 1102479..1103186 (-) 708 WP_037600497.1 response regulator YycF Regulator
  I6I02_RS04875 (I6I02_04875) - 1103472..1104239 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  I6I02_RS04880 (I6I02_04880) - 1104249..1105082 (+) 834 WP_198463941.1 transporter substrate-binding domain-containing protein -
  I6I02_RS04885 (I6I02_04885) - 1105100..1105798 (+) 699 WP_198463942.1 amino acid ABC transporter permease -
  I6I02_RS04890 (I6I02_04890) - 1105810..1106460 (+) 651 WP_037601175.1 amino acid ABC transporter permease -
  I6I02_RS04895 (I6I02_04895) - 1106651..1107418 (+) 768 WP_048675082.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50942.20 Da        Isoelectric Point: 5.1606

>NTDB_id=517358 I6I02_RS04865 WP_198463940.1 1101146..1102486(-) (vicK) [Streptococcus salivarius strain FDAARGOS_1045]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYNELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTNLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=517358 I6I02_RS04865 WP_198463940.1 1101146..1102486(-) (vicK) [Streptococcus salivarius strain FDAARGOS_1045]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTTTTTGTGGCTTTCTACTTTAT
TTTTCTTGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGAGTCAAGTCCCTAATGGCAGGTA
ACTATAATGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTT
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTATATGAGTGATGGAGTCAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAATGAATTGTTATCTAAGACTCCTGAGATT
CATTTGTCTCGTCGAGATGCCAACGATGAGTTTGTGACCCTACGCGTTAACTTTGCCCTTATTCGTAAAGAATCTGGTTT
TATCTCAGGTCTGGTTGCCGTCCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGGGAACGCCGACTCTTTGTATCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCTTATCTGGAGGCACTTGATGATGGTGCTCTTGACGAA
GAGATTGCCCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCAACCTTGACGTTGAAATGACTAATTTCACGGCCTTCATGACTTATATATTGAATC
GTTTTGATCAGATTAAGAGTCAAGAAACCAATACAGGTAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCGATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATCCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGTATTCCTA
AGAAGGATTTGCCGTTAATTTTTGACCGTTTTTACCGCGTTGATAAGGCTAGAAGTCGTGCTCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657