Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   I6H74_RS09665 Genome accession   NZ_CP066069
Coordinates   1954942..1955652 (-) Length   236 a.a.
NCBI ID   WP_003049952.1    Uniprot ID   A0A9X9SIG1
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949942..1960652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS09645 (I6H74_09640) - 1950127..1951143 (+) 1017 WP_115256787.1 IS30 family transposase -
  I6H74_RS09650 (I6H74_09645) - 1951828..1952703 (+) 876 WP_046177434.1 helix-turn-helix transcriptional regulator -
  I6H74_RS09655 (I6H74_09650) vicX 1952784..1953593 (-) 810 WP_115256786.1 MBL fold metallo-hydrolase Regulator
  I6H74_RS09660 (I6H74_09655) vicK 1953597..1954949 (-) 1353 WP_115256785.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6H74_RS09665 (I6H74_09660) vicR 1954942..1955652 (-) 711 WP_003049952.1 response regulator YycF Regulator
  I6H74_RS09670 (I6H74_09665) - 1955911..1956705 (+) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  I6H74_RS09675 (I6H74_09670) - 1956705..1957505 (+) 801 WP_115256784.1 transporter substrate-binding domain-containing protein -
  I6H74_RS09680 (I6H74_09675) - 1957519..1958220 (+) 702 WP_003057191.1 amino acid ABC transporter permease -
  I6H74_RS09685 (I6H74_09680) - 1958235..1958882 (+) 648 WP_046177436.1 amino acid ABC transporter permease -
  I6H74_RS09690 (I6H74_09685) - 1958978..1959973 (-) 996 WP_042357864.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27029.90 Da        Isoelectric Point: 4.9981

>NTDB_id=517120 I6H74_RS09665 WP_003049952.1 1954942..1955652(-) (vicR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEDEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=517120 I6H74_RS09665 WP_003049952.1 1954942..1955652(-) (vicR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGTGAAGCTGTTACCGTGTTTGAAGACGAAAAACCGGATTTAATTATTCTTGATTTGA
TGTTACCGGAATTGGACGGTCTTGAAGTGGCCAAAGAAATCCGTAAAACCAGTCATGTGCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGCCTTGAAATTGGGGCAGATGATTATGTTACCAAACCTTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377