Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I6H74_RS09660 Genome accession   NZ_CP066069
Coordinates   1953597..1954949 (-) Length   450 a.a.
NCBI ID   WP_115256785.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1948597..1959949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS09640 (I6H74_09635) rnc 1949226..1949918 (-) 693 WP_003057240.1 ribonuclease III -
  I6H74_RS09645 (I6H74_09640) - 1950127..1951143 (+) 1017 WP_115256787.1 IS30 family transposase -
  I6H74_RS09650 (I6H74_09645) - 1951828..1952703 (+) 876 WP_046177434.1 helix-turn-helix transcriptional regulator -
  I6H74_RS09655 (I6H74_09650) vicX 1952784..1953593 (-) 810 WP_115256786.1 MBL fold metallo-hydrolase Regulator
  I6H74_RS09660 (I6H74_09655) vicK 1953597..1954949 (-) 1353 WP_115256785.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6H74_RS09665 (I6H74_09660) vicR 1954942..1955652 (-) 711 WP_003049952.1 response regulator YycF Regulator
  I6H74_RS09670 (I6H74_09665) - 1955911..1956705 (+) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  I6H74_RS09675 (I6H74_09670) - 1956705..1957505 (+) 801 WP_115256784.1 transporter substrate-binding domain-containing protein -
  I6H74_RS09680 (I6H74_09675) - 1957519..1958220 (+) 702 WP_003057191.1 amino acid ABC transporter permease -
  I6H74_RS09685 (I6H74_09680) - 1958235..1958882 (+) 648 WP_046177436.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51417.98 Da        Isoelectric Point: 5.7383

>NTDB_id=517119 I6H74_RS09660 WP_115256785.1 1953597..1954949(-) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRGYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=517119 I6H74_RS09660 WP_115256785.1 1953597..1954949(-) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATTTGACCAAGGAGCAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCCCCAAGTTTTATCAAGGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGGCTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

PAS fold (PAS)

(95-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.188

92

0.673
  micB Streptococcus pneumoniae Cp1015

66.353

94.444

0.627