Detailed information NTG0516936

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: I6H78_RS02500
• Genome accession: NZ_CP066059
• Coordinates: 520680..521270 (-)
• Length: 196 a.a.
• NCBI ID: WP_198459840.1
• Uniprot ID: A0A7T4ITJ7
• Organism: Streptococcus oralis strain FDAARGOS_1021
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 515680..526270

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H78_RS02475 (I6H78_02475)	-	516371..517135 (-)	765	WP_001186014.1	ABC transporter ATP-binding protein	-
I6H78_RS02480 (I6H78_02480)	-	517135..518091 (-)	957	WP_061852739.1	branched-chain amino acid ABC transporter permease	-
I6H78_RS02485 (I6H78_02485)	-	518095..518964 (-)	870	WP_198459839.1	branched-chain amino acid ABC transporter permease	-
I6H78_RS02490 (I6H78_02490)	-	519084..520244 (-)	1161	WP_000726128.1	ABC transporter substrate-binding protein	-
I6H78_RS02495 (I6H78_02495)	-	520332..520601 (-)	270	WP_000462101.1	YlbG family protein	-
I6H78_RS02500 (I6H78_02500)	clpP	520680..521270 (-)	591	WP_198459840.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
I6H78_RS02505 (I6H78_02505)	upp	521451..522080 (-)	630	WP_000515974.1	uracil phosphoribosyltransferase	-
I6H78_RS02510 (I6H78_02510)	-	522169..522636 (-)	468	WP_000136990.1	deoxycytidylate deaminase	-
I6H78_RS02515 (I6H78_02515)	-	522655..523212 (-)	558	WP_000003901.1	TetR/AcrR family transcriptional regulator	-
I6H78_RS02520 (I6H78_02520)	-	523337..524182 (+)	846	WP_198459841.1	DegV family protein	-
I6H78_RS02525 (I6H78_02525)	-	524240..525421 (+)	1182	WP_332836292.1	NAD(P)/FAD-dependent oxidoreductase	-
I6H78_RS02530 (I6H78_02530)	-	525435..525956 (+)	522	WP_061852743.1	DUF1697 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21447.47 Da
• Isoelectric Point: 4.5022

>NTDB_id=516936 I6H78_RS02500 WP_198459840.1 520680..521270(-) (clpP) [Streptococcus oralis strain FDAARGOS_1021]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEKILADNSDK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=516936 I6H78_RS02500 WP_198459840.1 520680..521270(-) (clpP) [Streptococcus oralis strain FDAARGOS_1021]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGACATTTACTCTCGCCTTCTGAAAGACCGCAT
CATCATGCTAACAGGTCCAGTTGAAGACAACATGGCCAACTCCGTTATCGCCCAGTTGCTCTTCTTGGATGCCCAAGACA
GCACAAAAGATATTTACCTTTATGTCAATACACCTGGAGGATCTGTTTCAGCTGGTTTGGCAATCGTTGATACAATGAAC
TTTATCAAGGCAGATGTCCAAACAATCGTTATGGGGATGGCTGCATCCATGGGGACTGTCATTGCATCAAGTGGCGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGAACCCAACAGA
CAGATATGGCAATTGCTGCAGAACACTTGCTTAAAACCCGTAAGACCTTGGAAAAAATCCTTGCAGATAACTCTGATAAA
TCAGTTGAGCAAATTCATGCTGACGCTGAACGTGATTACTGGATGAGTGCCCAAGAAACACTTGAGTATGGTTTCATTGA
TGAAATCATGGCTAACAATTCTTTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A7T4ITJ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	95.918	100	0.959
clpP	Streptococcus pneumoniae D39	95.918	100	0.959
clpP	Streptococcus pneumoniae R6	95.918	100	0.959
clpP	Streptococcus pneumoniae TIGR4	95.918	100	0.959
clpP	Streptococcus pyogenes MGAS315	92.308	99.49	0.918
clpP	Streptococcus pyogenes JRS4	92.308	99.49	0.918
clpP	Streptococcus thermophilus LMD-9	90.256	99.49	0.898
clpP	Streptococcus thermophilus LMG 18311	90.256	99.49	0.898
clpP	Streptococcus mutans UA159	88.718	99.49	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.179	99.49	0.867
clpP	Lactococcus lactis subsp. cremoris KW2	86.667	99.49	0.862
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	57.292	97.959	0.561