Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I6H78_RS00465 Genome accession   NZ_CP066059
Coordinates   95329..96036 (+) Length   235 a.a.
NCBI ID   WP_000722058.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 90329..101036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS00440 (I6H78_00440) - 90627..91298 (+) 672 WP_000151555.1 GTP pyrophosphokinase family protein -
  I6H78_RS00445 (I6H78_00445) - 91282..92100 (+) 819 WP_198459574.1 NAD kinase -
  I6H78_RS00450 (I6H78_00450) - 92097..92993 (+) 897 WP_198459575.1 RluA family pseudouridine synthase -
  I6H78_RS00455 (I6H78_00455) pta 93037..94011 (+) 975 WP_084859882.1 phosphate acetyltransferase -
  I6H78_RS00460 (I6H78_00460) mutY 94094..95272 (+) 1179 WP_198459576.1 A/G-specific adenine glycosylase -
  I6H78_RS00465 (I6H78_00465) micA 95329..96036 (+) 708 WP_000722058.1 response regulator YycF Regulator
  I6H78_RS00470 (I6H78_00470) micB 96029..97378 (+) 1350 WP_061407142.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6H78_RS00475 (I6H78_00475) vicX 97380..98189 (+) 810 WP_198459577.1 MBL fold metallo-hydrolase Regulator
  I6H78_RS00480 (I6H78_00480) - 98224..98571 (-) 348 WP_198459578.1 thioredoxin -
  I6H78_RS00485 (I6H78_00485) - 98683..100401 (-) 1719 WP_198459579.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27005.85 Da        Isoelectric Point: 4.6177

>NTDB_id=516925 I6H78_RS00465 WP_000722058.1 95329..96036(+) (micA) [Streptococcus oralis strain FDAARGOS_1021]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=516925 I6H78_RS00465 WP_000722058.1 95329..96036(+) (micA) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTTGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCTGAGCAACCAGATATTATTATCCTTGACTTGA
TGCTACCTGAAATCGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTGCCGATTATCATGCTATCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGATGATTATGTTACAAAACCTTTCTCAAATCGTGA
GTTGCAGGCTCGTGTCAAGGCCCTGCTTCGTCGTACAGACCTGGTTTCAGTAGATAGCCAAGAGTCTGATGAGAAGAAGA
CGCAGCCTTTACAAATTGGTGATTTGGAAATCGTTCCAGATGCTTACGTGGCTAAGAAATATGGTGAGGAATTAGATTTG
ACCCACCGTGAGTTTGAACTTTTGTATCACTTGGCATCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTATGGGGATATGACTATTTTGGTGATGTTCGTACAGTGGACGTGACCATTAGACGCTTGCGTGAGAAAATAGAAGATA
CTCCAAGTCGTCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

43.723

98.298

0.43
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37