Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   I6H78_RS00470 Genome accession   NZ_CP066059
Coordinates   96029..97378 (+) Length   449 a.a.
NCBI ID   WP_061407142.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 91029..102378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS00445 (I6H78_00445) - 91282..92100 (+) 819 WP_198459574.1 NAD kinase -
  I6H78_RS00450 (I6H78_00450) - 92097..92993 (+) 897 WP_198459575.1 RluA family pseudouridine synthase -
  I6H78_RS00455 (I6H78_00455) pta 93037..94011 (+) 975 WP_084859882.1 phosphate acetyltransferase -
  I6H78_RS00460 (I6H78_00460) mutY 94094..95272 (+) 1179 WP_198459576.1 A/G-specific adenine glycosylase -
  I6H78_RS00465 (I6H78_00465) micA 95329..96036 (+) 708 WP_000722058.1 response regulator YycF Regulator
  I6H78_RS00470 (I6H78_00470) micB 96029..97378 (+) 1350 WP_061407142.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6H78_RS00475 (I6H78_00475) vicX 97380..98189 (+) 810 WP_198459577.1 MBL fold metallo-hydrolase Regulator
  I6H78_RS00480 (I6H78_00480) - 98224..98571 (-) 348 WP_198459578.1 thioredoxin -
  I6H78_RS00485 (I6H78_00485) - 98683..100401 (-) 1719 WP_198459579.1 phospho-sugar mutase -
  I6H78_RS00490 (I6H78_00490) - 100812..101966 (+) 1155 WP_198459580.1 DUF4352 domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51629.08 Da        Isoelectric Point: 4.6117

>NTDB_id=516926 I6H78_RS00470 WP_061407142.1 96029..97378(+) (micB) [Streptococcus oralis strain FDAARGOS_1021]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LMIDSQDVNGEFLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=516926 I6H78_RS00470 WP_061407142.1 96029..97378(+) (micB) [Streptococcus oralis strain FDAARGOS_1021]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGCGATTTTATTTTTATCTTGATTTTACTGGGCTTTATCCTGGTGGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTGAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTACAGGGCAGTACAGAAATCACCAATATTACCAATAACCTTAATGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAAAGACTGCATAGTATTCTTTCTTACATGACAGATGGAGT
GCTTGCGACTAATCGCCGTGGGCAGATTACCATGATTAACGACATGGCCAAGAAACAATTAGGTGTGCAGAAAGAGGATG
TCCTTAACAAAAGCATTTTAGAATTGCTTAAGATAGAGGATGAGTATGAACTGCGTGACCTGATTACACAGATTCCTGAG
TTGATGATTGATTCCCAAGATGTGAATGGTGAATTCCTGAGCCTTCGTGTACGTTTCGCTTTGGTTCGCCGTGAGTCTGG
ATTCATCTCGGGTTTGGTTGCCGTTTTACATGATACAACCGAGCAGGAGAAGGAAGAACGCGAACGGAGACTCTTCGTTT
CAAACGTGAGTCATGAGCTGAGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGAGCCTTGTAT
GATCCTGTAGCCCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATGCGACTACTCAGTTGGATGTGGAGTTGATTAACTTTACGGCCTTCATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGTCAGGATGACGAGAAAAAATATGAACTTGTTAGAGATTACCCAATAAACTCAGTTTGG
ATTGAGATTGATACCGATAAGATGACTCAGGTGATTGATAATATTCTTAACAATGCCATTAAGTACTCACCAGATGGTGG
CAAAATTACTGTTAGCATGAAGACCACTGACGACCAGATGATTTTATCCATCAAAGACCAAGGTTTAGGTATTCCAAAGC
AAGATTTGCCGAAGATTTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCTCAAGGTGGTACCGGTCTAGGT
CTGGCTATCGCAAAAGAAATCATTAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGCTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

88.838

97.773

0.869
  vicK Streptococcus mutans UA159

70.896

89.532

0.635