Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6H72_RS01620 Genome accession   NZ_CP066055
Coordinates   321948..322622 (+) Length   224 a.a.
NCBI ID   WP_198458164.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 316948..327622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS01595 (I6H72_01595) - 318454..319413 (+) 960 WP_198458161.1 ROK family glucokinase -
  I6H72_RS01600 (I6H72_01600) rplS 319563..319910 (+) 348 WP_003024326.1 50S ribosomal protein L19 -
  I6H72_RS01610 (I6H72_01610) - 320155..320913 (+) 759 WP_198458162.1 alpha/beta hydrolase -
  I6H72_RS01615 (I6H72_01615) - 321241..321684 (+) 444 WP_198458163.1 hypothetical protein -
  I6H72_RS01620 (I6H72_01620) ciaR 321948..322622 (+) 675 WP_198458164.1 response regulator transcription factor Regulator
  I6H72_RS01625 (I6H72_01625) ciaH 322612..323958 (+) 1347 WP_198458165.1 sensor histidine kinase Regulator
  I6H72_RS01630 (I6H72_01630) - 324390..325838 (-) 1449 WP_198458166.1 alpha-amylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25315.00 Da        Isoelectric Point: 4.2703

>NTDB_id=516831 I6H72_RS01620 WP_198458164.1 321948..322622(+) (ciaR) [Streptococcus constellatus strain FDAARGOS_1015]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKGLREKGVTTPILIMTA
KESLNDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLSYGDVTINLSTNTTLVDGNEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTTFANNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=516831 I6H72_RS01620 WP_198458164.1 321948..322622(+) (ciaR) [Streptococcus constellatus strain FDAARGOS_1015]
ATGATTAAGATTCTATTAGTAGAAGATGACCTTGGTTTATCTAACTCAGTATTTGATTTTTTGGATGATTTTGCAGATGT
CATGCAAGTTTTTGATGGTGAGGAAGGATTGTACGAAGCCGAAAGTGGTGTGTACGATCTTATCTTACTTGATTTGATGT
TACCGGAAAAAGACGGTTTTCAAGTATTGAAGGGATTACGTGAAAAAGGTGTTACAACACCGATATTGATTATGACAGCT
AAAGAGAGTTTGAATGATAAAGGACATGGCTTTGAGCTGGGAGCCGACGATTATTTGACCAAACCATTTTATTTGGAAGA
GTTAAAAATGCGGATTCAAGCTCTTTTGAAACGATCGGGCAAGTTTAATGAAAATACTCTTTCTTATGGCGATGTAACCA
TTAATTTGTCAACGAACACGACACTTGTAGATGGAAATGAAGTAGAGTTACTCGGAAAAGAATTTGATTTATTAGTATAT
TTCTTGCAGAATCAAAATGTTATTCTACCGAAGACGCAGATTTTCGATCGCTTATGGGGGTTTGATAGTGATACAACCAT
TTCAGTTGTAGAAGTTTATGTCTCAAAAATTCGGAAAAAATTGAAAGGGACGACCTTTGCGAATAATCTTCAAACACTTC
GCAGCGTCGGATATATTTTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

90.625

100

0.906
  ciaR Streptococcus pneumoniae D39

90.625

100

0.906
  ciaR Streptococcus pneumoniae R6

90.625

100

0.906
  ciaR Streptococcus pneumoniae TIGR4

90.625

100

0.906
  ciaR Streptococcus mutans UA159

88.789

99.554

0.884
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.648

100

0.402
  vicR Streptococcus mutans UA159

36.481

100

0.379
  covR Streptococcus salivarius strain HSISS4

36.123

100

0.366
  micA Streptococcus pneumoniae Cp1015

34.764

100

0.362