Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I6H72_RS00775 Genome accession   NZ_CP066055
Coordinates   146616..147317 (+) Length   233 a.a.
NCBI ID   WP_003035055.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 141616..152317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS00755 (I6H72_00755) ccpA 142547..143551 (+) 1005 WP_006270669.1 catabolite control protein A Regulator
  I6H72_RS00760 (I6H72_00760) - 143643..144641 (+) 999 WP_020997876.1 glycosyltransferase family 4 protein -
  I6H72_RS00765 (I6H72_00765) - 144643..145956 (+) 1314 WP_006268747.1 glycosyltransferase family 4 protein -
  I6H72_RS00770 (I6H72_00770) - 146010..146315 (+) 306 WP_198458408.1 hypothetical protein -
  I6H72_RS00775 (I6H72_00775) micA 146616..147317 (+) 702 WP_003035055.1 response regulator YycF Regulator
  I6H72_RS00780 (I6H72_00780) micB 147310..148662 (+) 1353 WP_006270686.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6H72_RS00785 (I6H72_00785) vicX 148664..149467 (+) 804 WP_003068695.1 MBL fold metallo-hydrolase Regulator
  I6H72_RS00790 (I6H72_00790) - 149501..149814 (+) 314 Protein_154 DUF454 family protein -
  I6H72_RS00795 (I6H72_00795) rnc 149950..150648 (+) 699 WP_003068697.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26868.85 Da        Isoelectric Point: 4.7415

>NTDB_id=516827 I6H72_RS00775 WP_003035055.1 146616..147317(+) (micA) [Streptococcus constellatus strain FDAARGOS_1015]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFNGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=516827 I6H72_RS00775 WP_003035055.1 146616..147317(+) (micA) [Streptococcus constellatus strain FDAARGOS_1015]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAATTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCAATGGTCGTGAAGCATTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGATAAAGTCATTGGTCTCGAAATCGGAGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTAATGACGCGTGAACATCTACTAGAAACGGTGTG
GGGATATGATTATTTTGGAGATGTTCGGACTGTTGATGTGACAATTCGCCGTTTGAGAGAGAAGATTGAGGATATTCCTA
GCCGACCAGAGTATATTTTAACACGGCGCGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

98.283

0.446
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  scnR Streptococcus mutans UA159

36.052

100

0.361