Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   I6H72_RS00780 Genome accession   NZ_CP066055
Coordinates   147310..148662 (+) Length   450 a.a.
NCBI ID   WP_006270686.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 142310..153662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS00755 (I6H72_00755) ccpA 142547..143551 (+) 1005 WP_006270669.1 catabolite control protein A Regulator
  I6H72_RS00760 (I6H72_00760) - 143643..144641 (+) 999 WP_020997876.1 glycosyltransferase family 4 protein -
  I6H72_RS00765 (I6H72_00765) - 144643..145956 (+) 1314 WP_006268747.1 glycosyltransferase family 4 protein -
  I6H72_RS00770 (I6H72_00770) - 146010..146315 (+) 306 WP_198458408.1 hypothetical protein -
  I6H72_RS00775 (I6H72_00775) micA 146616..147317 (+) 702 WP_003035055.1 response regulator YycF Regulator
  I6H72_RS00780 (I6H72_00780) micB 147310..148662 (+) 1353 WP_006270686.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6H72_RS00785 (I6H72_00785) vicX 148664..149467 (+) 804 WP_003068695.1 MBL fold metallo-hydrolase Regulator
  I6H72_RS00790 (I6H72_00790) - 149501..149814 (+) 314 Protein_154 DUF454 family protein -
  I6H72_RS00795 (I6H72_00795) rnc 149950..150648 (+) 699 WP_003068697.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51400.71 Da        Isoelectric Point: 4.7721

>NTDB_id=516828 I6H72_RS00780 WP_006270686.1 147310..148662(+) (micB) [Streptococcus constellatus strain FDAARGOS_1015]
MIDNIRQFVVSRDFVFVLLILGFILVITLLSLENRRDNIRIRRLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDVEDEYDLRDLITKVPV
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVGMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=516828 I6H72_RS00780 WP_006270686.1 147310..148662(+) (micB) [Streptococcus constellatus strain FDAARGOS_1015]
ATGATTGATAATATTAGACAATTTGTTGTATCAAGGGATTTTGTTTTTGTCTTACTTATTTTAGGATTTATTTTGGTCAT
TACGCTGCTCTCCTTGGAAAACAGACGTGATAATATTCGTATTCGCCGATTGAATCAAAAAGTGAAGGATTTAATCGCGG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGTCCGGAAATTACTGATATTACAAATAGTATCAATGACTTATCTGAG
GTAATTCGCCTAACGCATGAAAATTTAGAGCAAGAAACCAAACGCTTGTCTAGTATTTTGTCCTATATGACAGATGGCGT
TCTTGCGACCAATCGTCGTGGGCAGATTATTATGATTAATGATATGGCGACCAAGCAATTGGGAGTCAAAGAATCTGAAG
CACGAAAGATGAATATCTTAAAATTGTTGGATGTTGAAGACGAATATGATTTACGAGACTTGATTACGAAAGTTCCAGTG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCTGTGCTGCACGATACAACGGAGCAGGAGAAAGAGGAGCGTGAGCGGAGACTATTTGTTT
CCAATGTTAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGTGCCTTGTCA
GAACCAGTCGCACCAGATTTTATTAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGAATGGTTTCAGACTTGCTGAG
TTTGTCACGTATTGACAATGCTACCAGTCATTTGGATATTGAGCTGACGAATTTTACAGCTTTTATCACGTTTATTTTAA
ATCGTTTTGACAAAATCAGAAGTCAGAATGATGATAAAAAATATGAAATCATTCGTGATTACCCCATTAACTCCATCTGG
GTTGAAATTGATACGGATAAGATGACACAGGTTATTGATAATATCATCAATAATGCTATTAAATATTCTCCTGACGGCGG
TAAGATCACAGTGGGTATGAAAACAACCGAGACCCAAATGATTTTGTCTATATCAGATGAGGGCTTAGGAATTCCCAAAA
AAGATTTACCGAAAATTTTTGACCGCTTCTATCGTGTAGACAAAGCAAGAAGTCGTGCACAAGGTGGATCCGGATTAGGT
TTAGCTATTGCTAAGGAAATTATTAAGCAACATCACGGATTTATCTGGGCAAAGAGCGAGTATGGCAAAGGCTCAACCTT
TACTATTGTCCTGCCTTATGATAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.321

97.556

0.793
  vicK Streptococcus mutans UA159

70.905

90.889

0.644