Detailed information NTG0516626

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: I6I32_RS02440
• Genome accession: NZ_CP066041
• Coordinates: 495624..496214 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613466.1
• Uniprot ID: A0A3R9JXN4
• Organism: Streptococcus oralis strain FDAARGOS_1075
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 490624..501214

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I32_RS02415 (I6I32_02415)	-	491314..492078 (-)	765	WP_001186014.1	ABC transporter ATP-binding protein	-
I6I32_RS02420 (I6I32_02420)	-	492078..493034 (-)	957	WP_000856262.1	branched-chain amino acid ABC transporter permease	-
I6I32_RS02425 (I6I32_02425)	-	493038..493907 (-)	870	WP_000941413.1	branched-chain amino acid ABC transporter permease	-
I6I32_RS02430 (I6I32_02430)	-	494027..495187 (-)	1161	WP_070656982.1	ABC transporter substrate-binding protein	-
I6I32_RS02435 (I6I32_02435)	-	495276..495545 (-)	270	WP_198464833.1	YlbG family protein	-
I6I32_RS02440 (I6I32_02440)	clpP	495624..496214 (-)	591	WP_000613466.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
I6I32_RS02445 (I6I32_02445)	upp	496387..497016 (-)	630	WP_000515974.1	uracil phosphoribosyltransferase	-
I6I32_RS02450 (I6I32_02450)	-	497105..497572 (-)	468	WP_000136994.1	deoxycytidylate deaminase	-
I6I32_RS02455 (I6I32_02455)	-	497591..498148 (-)	558	WP_000003897.1	TetR/AcrR family transcriptional regulator	-
I6I32_RS02460 (I6I32_02460)	-	498273..499118 (+)	846	WP_198464834.1	DegV family protein	-
I6I32_RS02465 (I6I32_02465)	-	499176..500351 (+)	1176	WP_198464835.1	NAD(P)/FAD-dependent oxidoreductase	-
I6I32_RS02470 (I6I32_02470)	-	500370..500825 (+)	456	WP_198464836.1	8-oxo-dGTP diphosphatase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21389.39 Da
• Isoelectric Point: 4.4829

>NTDB_id=516626 I6I32_RS02440 WP_000613466.1 495624..496214(-) (clpP) [Streptococcus oralis strain FDAARGOS_1075]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=516626 I6I32_RS02440 WP_000613466.1 495624..496214(-) (clpP) [Streptococcus oralis strain FDAARGOS_1075]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGACATATACTCTCGTCTTCTGAAAGACCGCAT
CATCATGCTAACAGGTCCAGTTGAAGACAACATGGCCAACTCCGTTATCGCCCAGTTGCTCTTCTTGGATGCCCAAGATA
GCACAAAAGATATTTACCTTTATGTCAACACACCTGGAGGTTCTGTTTCAGCTGGTTTGGCAATCGTTGATACTATGAAC
TTTATCAAGGCAGATGTCCAAACCATCGTGATGGGAATGGCTGCATCTATGGGGACTGTTATTGCATCAAGTGGAGCAAA
AGGCAAACGCTTCATGCTTCCAAATGCAGAATACATGATTCACCAACCAATGGGTGGAACCGGTGGTGGTACCCAACAGA
CAGATATGGCAATCGCTGCAGAACACTTGCTTAAAACTCGTAAGACTTTGGAGCAAATCCTTGCAGATAACTCTGGTAAA
TCAGTTGAGCAAATTCATGCTGACGCTGAACGTGATTACTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCTAACAATTCTTTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A3R9JXN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	95.918	100	0.959
clpP	Streptococcus pneumoniae R6	95.918	100	0.959
clpP	Streptococcus pneumoniae TIGR4	95.918	100	0.959
clpP	Streptococcus pneumoniae D39	95.918	100	0.959
clpP	Streptococcus pyogenes JRS4	92.308	99.49	0.918
clpP	Streptococcus pyogenes MGAS315	92.308	99.49	0.918
clpP	Streptococcus thermophilus LMD-9	91.282	99.49	0.908
clpP	Streptococcus thermophilus LMG 18311	91.282	99.49	0.908
clpP	Streptococcus mutans UA159	88.718	99.49	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.692	99.49	0.872
clpP	Lactococcus lactis subsp. cremoris KW2	87.179	99.49	0.867
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	57.292	97.959	0.561