Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   I6I32_RS01740 Genome accession   NZ_CP066041
Coordinates   351985..352638 (-) Length   217 a.a.
NCBI ID   WP_198464758.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 346985..357638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS01720 (I6I32_01720) rplT 348367..348726 (-) 360 WP_000124830.1 50S ribosomal protein L20 -
  I6I32_RS01725 (I6I32_01725) rpmI 348778..348978 (-) 201 WP_001125942.1 50S ribosomal protein L35 -
  I6I32_RS01730 (I6I32_01730) infC 349011..349541 (-) 531 WP_000848184.1 translation initiation factor IF-3 -
  I6I32_RS01735 (I6I32_01735) comEC/celB 349761..352001 (-) 2241 WP_198464757.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  I6I32_RS01740 (I6I32_01740) comEA/celA/cilE 351985..352638 (-) 654 WP_198464758.1 helix-hairpin-helix domain-containing protein Machinery gene
  I6I32_RS01745 (I6I32_01745) - 352706..353275 (-) 570 WP_198464759.1 GNAT family N-acetyltransferase -
  I6I32_RS01750 (I6I32_01750) ald 353451..354563 (+) 1113 WP_198464760.1 alanine dehydrogenase -
  I6I32_RS01755 (I6I32_01755) - 354616..355602 (-) 987 WP_198464761.1 PhoH family protein -
  I6I32_RS01760 (I6I32_01760) - 355683..355898 (-) 216 WP_001232084.1 YozE family protein -
  I6I32_RS01765 (I6I32_01765) - 355895..356500 (-) 606 WP_198464762.1 GrpB family protein -
  I6I32_RS01770 (I6I32_01770) cvfB 356512..357366 (-) 855 WP_198464763.1 RNA-binding virulence regulatory protein CvfB -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23288.41 Da        Isoelectric Point: 5.2518

>NTDB_id=516624 I6I32_RS01740 WP_198464758.1 351985..352638(-) (comEA/celA/cilE) [Streptococcus oralis strain FDAARGOS_1075]
MEAIIEKIKEYKIIVICAGLGLALGGFFLLKPTSQTSVKETNLQAEVAAVSKDSSSEKEVNKEEKEESSEQDLITVDVKG
AVKSPGLYDLPVGSRVHDAVQKAGGLTEEADSKLLNLAQKISDEALVYVPTKGEEEAASQQAASGTSPSTSKEKKVNLNK
ASLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 654 bp        

>NTDB_id=516624 I6I32_RS01740 WP_198464758.1 351985..352638(-) (comEA/celA/cilE) [Streptococcus oralis strain FDAARGOS_1075]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATTTGTGCTGGTTTGGGTTTGGCCTTGGGCGGATT
TTTCCTACTAAAGCCAACTTCACAAACATCTGTGAAAGAAACAAACTTGCAGGCTGAAGTTGCAGCTGTTTCAAAGGATT
CATCGTCTGAAAAAGAAGTGAACAAGGAAGAAAAGGAAGAGTCTTCTGAACAAGATCTAATAACAGTAGATGTCAAGGGT
GCTGTCAAATCGCCAGGGCTTTATGACTTACCAGTAGGGAGTCGGGTTCATGATGCCGTTCAGAAGGCAGGTGGATTGAC
AGAGGAGGCAGATAGTAAGTTGCTCAATCTCGCTCAGAAAATCAGTGACGAGGCTCTTGTCTATGTTCCAACTAAGGGAG
AAGAAGAAGCGGCTAGTCAGCAGGCTGCCTCTGGAACGTCTCCTTCGACAAGTAAAGAAAAGAAGGTCAATCTCAATAAA
GCTAGCCTGGAAGAACTCAAGCAAGTCAAAGGCTTGGGAGGAAAAAGAGCCCAGGATATTATCGATCATCGTGAGACGAA
TGGCAAATTCAAGTCGGTGGATGAATTAAAGAAGGTCTCTGGCATTGGCGCTAAGACCATAGAAAAGCTAAAAGATTATG
TCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-127)

Helix-hairpin-helix motif (HHH_3)

(152-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

89.862

100

0.899
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

89.401

100

0.894
  comEA/celA/cilE Streptococcus pneumoniae R6

88.479

100

0.885
  comEA/celA/cilE Streptococcus pneumoniae D39

88.479

100

0.885
  comEA/celA/cilE Streptococcus pneumoniae Rx1

88.479

100

0.885
  comEA/celA/cilE Streptococcus mitis SK321

85.253

100

0.853
  comEA Lactococcus lactis subsp. cremoris KW2

41.85

100

0.438