Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   I6H76_RS08165 Genome accession   NZ_CP065994
Coordinates   1592259..1592849 (+) Length   196 a.a.
NCBI ID   WP_006532857.1    Uniprot ID   A0A380KQE3
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1590253..1599809 1592259..1592849 within 0


Gene organization within MGE regions


Location: 1590253..1599809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS08155 (I6H76_08155) - 1590253..1591122 (-) 870 WP_006532859.1 LysR family transcriptional regulator -
  I6H76_RS08160 (I6H76_08160) - 1591236..1592129 (+) 894 WP_006532858.1 DMT family transporter -
  I6H76_RS08165 (I6H76_08165) clpP 1592259..1592849 (+) 591 WP_006532857.1 ATP-dependent Clp protease proteolytic subunit Regulator
  I6H76_RS08170 (I6H76_08170) - 1592952..1593392 (+) 441 WP_006532856.1 YlbF family regulator -
  I6H76_RS08175 (I6H76_08175) - 1593385..1593636 (+) 252 WP_006532855.1 DUF2129 domain-containing protein -
  I6H76_RS08180 (I6H76_08180) - 1593748..1594929 (+) 1182 WP_006532854.1 ABC transporter substrate-binding protein -
  I6H76_RS08185 (I6H76_08185) - 1594982..1595866 (+) 885 WP_006532853.1 branched-chain amino acid ABC transporter permease -
  I6H76_RS08190 (I6H76_08190) - 1595870..1596823 (+) 954 WP_006532852.1 branched-chain amino acid ABC transporter permease -
  I6H76_RS08195 (I6H76_08195) - 1596823..1597587 (+) 765 WP_006532851.1 ABC transporter ATP-binding protein -
  I6H76_RS08200 (I6H76_08200) - 1597587..1598297 (+) 711 WP_006532850.1 ABC transporter ATP-binding protein -
  I6H76_RS08205 (I6H76_08205) - 1598431..1599090 (+) 660 WP_006532849.1 CBS domain-containing protein -
  I6H76_RS08210 (I6H76_08210) tmk 1599183..1599809 (+) 627 WP_006532848.1 dTMP kinase -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21496.42 Da        Isoelectric Point: 4.3303

>NTDB_id=516151 I6H76_RS08165 WP_006532857.1 1592259..1592849(+) (clpP) [Streptococcus infantarius strain FDAARGOS_1019]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVDDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQSDMAIAAEHLLKTRQNLEQILADNSGQ
SLEKVHADAERDNWMSAQETLEYGFIDEIMVNNELN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=516151 I6H76_RS08165 WP_006532857.1 1592259..1592849(+) (clpP) [Streptococcus infantarius strain FDAARGOS_1019]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGCGGTGAACGCTCATATGATATTTACTCACGTCTTTTGAAAGATCGTAT
CATCATGTTGACTGGACCAGTTGATGACAATATGGCAAACTCTATCATTGCTCAACTATTGTTCCTTGATGCACAAGATA
ATACAAAAGATATTTACCTTTATGTTAATACACCTGGTGGATCAGTTTCAGCTGGTCTTGCTATTGTAGATACAATGAAC
TTCATTAAATCTGATGTTCAAACTATCGTTATGGGTATGGCAGCATCAATGGGAACAATCATTGCTTCATCAGGTACAAA
AGGTAAACGATTCATGTTGCCAAACGCTGAATATATGATTCACCAACCAATGGGTGGTACTGGTGGCGGTACTCAACAAA
GCGATATGGCTATTGCTGCTGAACACCTTTTGAAAACACGTCAAAACTTGGAACAAATTTTGGCTGACAACTCAGGTCAA
AGTTTGGAAAAAGTTCACGCTGATGCTGAACGTGATAACTGGATGAGCGCTCAAGAAACTCTTGAATATGGCTTCATCGA
TGAAATTATGGTTAACAACGAATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KQE3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus thermophilus LMG 18311

95.385

99.49

0.949
  clpP Streptococcus thermophilus LMD-9

95.385

99.49

0.949
  clpP Streptococcus pneumoniae Rx1

92.857

100

0.929
  clpP Streptococcus pneumoniae D39

92.857

100

0.929
  clpP Streptococcus pneumoniae R6

92.857

100

0.929
  clpP Streptococcus pneumoniae TIGR4

92.857

100

0.929
  clpP Streptococcus pyogenes JRS4

88.776

100

0.888
  clpP Streptococcus pyogenes MGAS315

88.776

100

0.888
  clpP Streptococcus mutans UA159

87.755

100

0.878
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.245

100

0.872
  clpP Lactococcus lactis subsp. cremoris KW2

86.735

100

0.867
  clpP Bacillus subtilis subsp. subtilis str. 168

58.763

98.98

0.582
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.421

96.939

0.566