Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   JAN99_RS06895 Genome accession   NZ_CP065927
Coordinates   1410073..1410783 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm9ST603     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1405073..1415783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JAN99_RS06880 (JAN99_06875) rnc 1406780..1407472 (-) 693 WP_002990670.1 ribonuclease III -
  JAN99_RS06885 (JAN99_06880) vicX 1407915..1408724 (-) 810 WP_023612763.1 MBL fold metallo-hydrolase Regulator
  JAN99_RS06890 (JAN99_06885) vicK 1408728..1410080 (-) 1353 WP_002985643.1 cell wall metabolism sensor histidine kinase VicK Regulator
  JAN99_RS06895 (JAN99_06890) vicR 1410073..1410783 (-) 711 WP_002985645.1 response regulator YycF Regulator
  JAN99_RS06900 (JAN99_06895) - 1410945..1411979 (-) 1035 WP_161230152.1 DUF3114 domain-containing protein -
  JAN99_RS06905 (JAN99_06900) - 1412035..1413282 (-) 1248 WP_111693060.1 AMP-binding protein -
  JAN99_RS06910 (JAN99_06905) - 1413239..1414387 (-) 1149 WP_111693059.1 acetyl-CoA C-acyltransferase -
  JAN99_RS06915 (JAN99_06910) - 1414782..1414931 (-) 150 WP_002990686.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=515378 JAN99_RS06895 WP_002985645.1 1410073..1410783(-) (vicR) [Streptococcus pyogenes strain emm9ST603]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=515378 JAN99_RS06895 WP_002985645.1 1410073..1410783(-) (vicR) [Streptococcus pyogenes strain emm9ST603]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364