Detailed information NTG0514250

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: STMM8_RS01840
• Genome accession: NZ_CP065787
• Coordinates: 335504..336094 (+)
• Length: 196 a.a.
• NCBI ID: WP_002949732.1
• Uniprot ID: Q5M5U4
• Organism: Streptococcus thermophilus strain MM8
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 330504..341094

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM8_RS01810 (STMM8_01805)	-	330883..331476 (+)	594	Protein_304	cation transporting ATPase C-terminal domain-containing protein	-
STMM8_RS01815 (STMM8_01810)	-	331780..332874 (+)	1095	WP_002946733.1	cystathionine gamma-synthase	-
STMM8_RS01820 (STMM8_01815)	-	332885..334048 (+)	1164	WP_022096631.1	MalY/PatB family protein	-
STMM8_RS01825 (STMM8_01820)	-	334124..334291 (+)	168	WP_042798881.1	hypothetical protein	-
STMM8_RS01830 (STMM8_01825)	-	334332..334607 (+)	276	WP_011225506.1	hypothetical protein	-
STMM8_RS01835 (STMM8_01830)	upp	334737..335366 (+)	630	WP_002946740.1	uracil phosphoribosyltransferase	-
STMM8_RS01840 (STMM8_01835)	clpP	335504..336094 (+)	591	WP_002949732.1	ATP-dependent Clp protease proteolytic subunit	Regulator
STMM8_RS01845 (STMM8_01840)	-	336181..336630 (+)	450	WP_014621174.1	YlbF family regulator	-
STMM8_RS01850 (STMM8_01845)	-	336623..336904 (+)	282	WP_002945119.1	YlbG family protein	-
STMM8_RS01855 (STMM8_01850)	-	337061..338236 (+)	1176	WP_022096632.1	ABC transporter substrate-binding protein	-
STMM8_RS01860 (STMM8_01855)	-	338280..339164 (+)	885	WP_011225509.1	branched-chain amino acid ABC transporter permease	-
STMM8_RS01865 (STMM8_01860)	-	339168..340118 (+)	951	WP_011225510.1	branched-chain amino acid ABC transporter permease	-
STMM8_RS01870 (STMM8_01865)	-	340121..340885 (+)	765	WP_002947187.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21577.62 Da
• Isoelectric Point: 4.4829

>NTDB_id=514250 STMM8_RS01840 WP_002949732.1 335504..336094(+) (clpP) [Streptococcus thermophilus strain MM8]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPIEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILADNSGQ
PIEKVHVDAERDNWMSAQETLEYGFIDEIMTNNQLK

Nucleotide

• Length: 591 bp

>NTDB_id=514250 STMM8_RS01840 WP_002949732.1 335504..336094(+) (clpP) [Streptococcus thermophilus strain MM8]
ATGATTCCGGTAGTTATTGAACAAACATCACGTGGTGAACGTTCTTATGACATTTACTCACGTTTGCTCAAGGATCGTAT
TATCATGTTAACAGGTCCTATAGAAGATAATATGGCAAACTCAATTATCGCTCAACTCTTGTTCTTGGATGCTCAAGACA
ATACAAAAGATATCTATCTGTATGTTAATACACCTGGTGGGTCAGTTTCAGCAGGCCTTGCCATTGTTGATACAATGAAC
TTCATCAAGTCTGATGTTCAAACCATCGTTATGGGGATGGCAGCATCAATGGGGACAATTATCGCTTCAAGCGGTACCAA
AGGTAAACGTTTCATGTTGCCAAATGCAGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACTCAACAAA
CAGATATGGCTATCGCTGCTGAACACTTGCTCAAGACTCGTAATAACTTGGAGCAAATCTTGGCTGATAATTCTGGTCAG
CCAATTGAAAAGGTTCATGTCGATGCTGAACGTGATAATTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTCATTGA
TGAAATCATGACCAACAACCAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: Q5M5U4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	100	100	1
clpP	Streptococcus thermophilus LMD-9	100	100	1
clpP	Streptococcus pneumoniae D39	92.821	99.49	0.923
clpP	Streptococcus pneumoniae R6	92.821	99.49	0.923
clpP	Streptococcus pneumoniae TIGR4	92.821	99.49	0.923
clpP	Streptococcus pneumoniae Rx1	92.821	99.49	0.923
clpP	Streptococcus pyogenes MGAS315	89.796	100	0.898
clpP	Streptococcus pyogenes JRS4	89.796	100	0.898
clpP	Streptococcus mutans UA159	87.755	100	0.878
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.245	100	0.872
clpP	Lactococcus lactis subsp. cremoris KW2	86.735	100	0.867
clpP	Bacillus subtilis subsp. subtilis str. 168	59.184	100	0.592
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577