Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   I6G77_RS06300 Genome accession   NZ_CP065739
Coordinates   1212027..1212608 (-) Length   193 a.a.
NCBI ID   WP_000991609.1    Uniprot ID   A0A853X8N5
Organism   Bacillus tropicus strain FDAARGOS_920     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1209746..1226160 1212027..1212608 within 0


Gene organization within MGE regions


Location: 1209746..1226160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G77_RS06290 (I6G77_06290) - 1209746..1210951 (-) 1206 WP_000370618.1 quaternary amine ABC transporter ATP-binding protein -
  I6G77_RS06295 (I6G77_06295) - 1211123..1211980 (+) 858 WP_042515006.1 glycine betaine ABC transporter substrate-binding protein -
  I6G77_RS06300 (I6G77_06300) clpP 1212027..1212608 (-) 582 WP_000991609.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  I6G77_RS06305 (I6G77_06305) - 1212630..1213316 (-) 687 WP_042515005.1 RNA polymerase subunit sigma-70 -
  I6G77_RS06310 (I6G77_06310) - 1213460..1213780 (+) 321 WP_042515004.1 2Fe-2S iron-sulfur cluster-binding protein -
  I6G77_RS06315 (I6G77_06315) rpiA 1213785..1214447 (+) 663 WP_042515003.1 ribose 5-phosphate isomerase A -
  I6G77_RS06320 (I6G77_06320) - 1214554..1214988 (+) 435 WP_000555787.1 GNAT family N-acetyltransferase -
  I6G77_RS06325 (I6G77_06325) - 1215119..1216486 (-) 1368 WP_042515002.1 lytic polysaccharide monooxygenase -
  I6G77_RS06330 (I6G77_06330) - 1216844..1218037 (-) 1194 WP_042515001.1 macrolide family glycosyltransferase -
  I6G77_RS06335 (I6G77_06335) - 1218093..1218773 (-) 681 WP_042515000.1 formylglycine-generating enzyme family protein -
  I6G77_RS06340 (I6G77_06340) - 1218919..1219422 (-) 504 WP_042514999.1 DNA topology modulation protein -
  I6G77_RS06345 (I6G77_06345) - 1219444..1219830 (-) 387 WP_002194813.1 DUF2809 domain-containing protein -
  I6G77_RS06350 (I6G77_06350) - 1219896..1220603 (-) 708 WP_033691753.1 class I SAM-dependent methyltransferase -
  I6G77_RS06355 (I6G77_06355) - 1220625..1220978 (-) 354 WP_000648514.1 MmcQ/YjbR family DNA-binding protein -
  I6G77_RS06360 (I6G77_06360) - 1220981..1221397 (-) 417 WP_001981059.1 GNAT family N-acetyltransferase -
  I6G77_RS06365 (I6G77_06365) - 1221827..1223212 (+) 1386 WP_042514998.1 S-layer homology domain-containing protein -
  I6G77_RS06370 (I6G77_06370) - 1223215..1223427 (+) 213 WP_001981065.1 DUF3006 domain-containing protein -
  I6G77_RS06375 (I6G77_06375) - 1223492..1224298 (-) 807 WP_000540642.1 GH25 family lysozyme -
  I6G77_RS06380 (I6G77_06380) - 1224567..1224983 (-) 417 WP_033691754.1 GNAT family N-acetyltransferase -
  I6G77_RS06385 (I6G77_06385) - 1225016..1225387 (-) 372 WP_042514996.1 hypothetical protein -
  I6G77_RS06390 (I6G77_06390) - 1225384..1226160 (-) 777 WP_042514995.1 serine hydrolase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21192.49 Da        Isoelectric Point: 5.3394

>NTDB_id=513764 I6G77_RS06300 WP_000991609.1 1212027..1212608(-) (clpP) [Bacillus tropicus strain FDAARGOS_920]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=513764 I6G77_RS06300 WP_000991609.1 1212027..1212608(-) (clpP) [Bacillus tropicus strain FDAARGOS_920]
ATGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
CCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCCGGCGGATCAACGACAGCGGGATTTGCTATATTAGATACA
ATGAATTTAATTAAACCTGATGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCGCTTGGTGGTGCAAAAGGGCAGGCAA
CAGAAATTGAAATAACAGCAAAAAGGATATTGAAGTTAAAGCATGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACCGCAGAAGAAGCAAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A853X8N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.196

97.927

0.658
  clpP Streptococcus pyogenes JRS4

56.085

97.927

0.549
  clpP Streptococcus pyogenes MGAS315

56.085

97.927

0.549
  clpP Streptococcus pneumoniae R6

55.208

99.482

0.549
  clpP Streptococcus pneumoniae TIGR4

55.208

99.482

0.549
  clpP Streptococcus pneumoniae Rx1

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMG 18311

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMD-9

55.208

99.482

0.549
  clpP Streptococcus pneumoniae D39

55.208

99.482

0.549
  clpP Streptococcus mutans UA159

53.968

97.927

0.528
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

50.265

97.927

0.492