Detailed information NTG0513320

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: I6G42_RS09050
• Genome accession: NZ_CP065707
• Coordinates: 1845914..1846504 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613470.1
• Uniprot ID: A0A139PFB2
• Organism: Streptococcus oralis strain FDAARGOS_885
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1840914..1851504

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G42_RS09025 (I6G42_09025)	-	1841605..1842369 (-)	765	WP_038805585.1	ABC transporter ATP-binding protein	-
I6G42_RS09030 (I6G42_09030)	-	1842369..1843325 (-)	957	WP_038805586.1	branched-chain amino acid ABC transporter permease	-
I6G42_RS09035 (I6G42_09035)	-	1843329..1844198 (-)	870	WP_038805587.1	branched-chain amino acid ABC transporter permease	-
I6G42_RS09040 (I6G42_09040)	-	1844317..1845477 (-)	1161	WP_000726138.1	ABC transporter substrate-binding protein	-
I6G42_RS09045 (I6G42_09045)	-	1845566..1845835 (-)	270	WP_000462107.1	YlbG family protein	-
I6G42_RS09050 (I6G42_09050)	clpP	1845914..1846504 (-)	591	WP_000613470.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
I6G42_RS09055 (I6G42_09055)	upp	1846685..1847314 (-)	630	WP_025169005.1	uracil phosphoribosyltransferase	-
I6G42_RS09060 (I6G42_09060)	-	1847403..1847870 (-)	468	WP_038805588.1	deoxycytidylate deaminase	-
I6G42_RS09065 (I6G42_09065)	-	1847889..1848446 (-)	558	WP_038805589.1	TetR/AcrR family transcriptional regulator	-
I6G42_RS09070 (I6G42_09070)	-	1848571..1849416 (+)	846	WP_038805590.1	DegV family protein	-
I6G42_RS09075 (I6G42_09075)	-	1849474..1850655 (+)	1182	WP_038805672.1	NAD(P)/FAD-dependent oxidoreductase	-
I6G42_RS09080 (I6G42_09080)	-	1850669..1851190 (+)	522	WP_038805591.1	DUF1697 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21348.39 Da
• Isoelectric Point: 4.5654

>NTDB_id=513320 I6G42_RS09050 WP_000613470.1 1845914..1846504(-) (clpP) [Streptococcus oralis strain FDAARGOS_885]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILATNSGK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNSLS

Nucleotide

• Length: 591 bp

>NTDB_id=513320 I6G42_RS09050 WP_000613470.1 1845914..1846504(-) (clpP) [Streptococcus oralis strain FDAARGOS_885]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGACATTTACTCTCGCCTTCTGAAAGACCGCAT
CATCATGCTAACAGGTCCAGTTGAAGACAACATGGCCAACTCCGTTATCGCCCAGTTGCTCTTCTTGGATGCCCAAGACA
GCACAAAAGATATTTACCTTTATGTCAATACACCTGGAGGATCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACTATCGTTATGGGAATGGCTGCATCCATGGGGACTGTCATAGCATCAAGTGGAGCAAA
AGGCAAACGCTTCATGCTTCCAAATGCAGAGTACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAGA
CAGATATGGCAATCGCTGCAGAGCACTTGCTCAAAACTCGTAAGACTTTGGAGCAAATCCTTGCGACTAACTCAGGTAAA
TCAGTTGAGCAAATTCATGCAGATGCAGAACGTGATTACTGGATGAGTGCCCAAGAAACGCTCGAATATGGCTTCATTGA
TGAAATCATGGCTAACAATTCTTTGAGCTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A139PFB2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	95.408	100	0.954
clpP	Streptococcus pneumoniae D39	95.408	100	0.954
clpP	Streptococcus pneumoniae R6	95.408	100	0.954
clpP	Streptococcus pneumoniae TIGR4	95.408	100	0.954
clpP	Streptococcus pyogenes MGAS315	92.308	99.49	0.918
clpP	Streptococcus pyogenes JRS4	92.308	99.49	0.918
clpP	Streptococcus thermophilus LMD-9	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	90.769	99.49	0.903
clpP	Streptococcus mutans UA159	88.205	99.49	0.878
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.179	99.49	0.867
clpP	Lactococcus lactis subsp. cremoris KW2	86.667	99.49	0.862
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	57.292	97.959	0.561