Detailed information NTG0513280

Bioinformatically predicted

Overview

• Name: comGB/cglB
• Type: Machinery gene
• Locus tag: I6G42_RS03315
• Genome accession: NZ_CP065707
• Coordinates: 650473..651489 (+)
• Length: 338 a.a.
• NCBI ID: WP_068981894.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_885
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 645473..656489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G42_RS03295 (I6G42_03295)	-	645891..647708 (+)	1818	WP_038804055.1	acyltransferase family protein	-
I6G42_RS03300 (I6G42_03300)	nagA	647849..649000 (+)	1152	WP_038804054.1	N-acetylglucosamine-6-phosphate deacetylase	-
I6G42_RS03305 (I6G42_03305)	-	649149..649514 (+)	366	WP_000286399.1	DUF1033 family protein	-
I6G42_RS03310 (I6G42_03310)	comGA/cglA/cilD	649584..650525 (+)	942	WP_038804053.1	competence type IV pilus ATPase ComGA	Machinery gene
I6G42_RS03315 (I6G42_03315)	comGB/cglB	650473..651489 (+)	1017	WP_068981894.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6G42_RS03320 (I6G42_03320)	comGC/cglC	651491..651814 (+)	324	WP_038804052.1	competence type IV pilus major pilin ComGC	Machinery gene
I6G42_RS03325 (I6G42_03325)	comGD/cglD	651777..652211 (+)	435	WP_038804051.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6G42_RS03330 (I6G42_03330)	comGE/cglE	652174..652476 (+)	303	WP_265101009.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6G42_RS03335 (I6G42_03335)	comGF/cglF	652439..652900 (+)	462	WP_038804049.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6G42_RS03340 (I6G42_03340)	comGG	652878..653290 (+)	413	Protein_646	competence type IV pilus minor pilin ComGG	-
I6G42_RS03345 (I6G42_03345)	-	653323..653913 (+)	591	WP_038804047.1	class I SAM-dependent methyltransferase	-
I6G42_RS03350 (I6G42_03350)	comYH	653972..654925 (+)	954	WP_038804046.1	class I SAM-dependent methyltransferase	Machinery gene
I6G42_RS03355 (I6G42_03355)	-	654975..656165 (+)	1191	WP_038804045.1	acetate kinase	-

Sequence

Protein

• Length: 338 a.a.
• Molecular weight: 38555.71 Da
• Isoelectric Point: 9.7714

>NTDB_id=513280 I6G42_RS03315 WP_068981894.1 650473..651489(+) (comGB/cglB) [Streptococcus oralis strain FDAARGOS_885]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVTQMHQGLSQGKSFSEMMDSLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRGSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAKALQNGREFSQTIARYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide

• Length: 1017 bp

>NTDB_id=513280 I6G42_RS03315 WP_068981894.1 650473..651489(+) (comGB/cglB) [Streptococcus oralis strain FDAARGOS_885]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCCTGTTTAA
CAATCTCTTCTCCAGTGGTTTTCATTTGGTGGAAATTATTTCTTTCTTGGGGAGAAGTGCCTTGCTAGAAAAGGACTATG
TGACACAGATGCACCAAGGGCTGTCTCAGGGGAAATCCTTTTCAGAGATGATGGACAGCTTGGGTTTTTCAAGTGCTATT
GTGACCCAATTATCTCTAGCTGAAGTTCATGGGAATCTTCATCTGAGTTTGGGAAAGATAGAAGAATATTTGGATAATTT
GGCCAAGGTTAAGAAAAAGTTAATCGAAGTGGCGACCTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GATTGAGAAACTATCTACTACCCCAACTGGACAGTAGCAATATTGCCACCCAAATCATCGGCAATCTGCCACAAATTTTT
CTGGGACTAGTGCTGGTTTGCTCTCTATCTTTACTTTTAGCTCTCACTTTCTACAAAAGAGGTTCTAAGATGCGGGTCTT
CTCGATGTTAGCACGGATTCCCTTTCTTGGAATATTTGTCCAGACCTATCTGACAGCTTATTATGCGCGTGAATGGGGAA
ATATGATTTCGCAGGGAATGGAGCTGACGCAGATTTTTCAGATCATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTAAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAGCGAGATATCCATTCTTTAAGAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTAGGGAGTGAGTTGGAAATCTACGCAGAAAAGACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACTATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (24-141)

• Type II secretion system (T2SS), protein F (T2SSF) (209-329)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB/cglB	Streptococcus mitis SK321	93.491	100	0.935
comGB/cglB	Streptococcus mitis NCTC 12261	93.491	100	0.935
comGB/cglB	Streptococcus pneumoniae Rx1	90.828	100	0.908
comGB/cglB	Streptococcus pneumoniae D39	90.828	100	0.908
comGB/cglB	Streptococcus pneumoniae R6	90.828	100	0.908
comGB/cglB	Streptococcus pneumoniae TIGR4	90.828	100	0.908
comYB	Streptococcus gordonii str. Challis substr. CH1	73.512	99.408	0.731
comYB	Streptococcus mutans UA140	59.561	94.379	0.562
comYB	Streptococcus mutans UA159	59.561	94.379	0.562
comGB	Lactococcus lactis subsp. cremoris KW2	52.071	100	0.521