Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   I6G42_RS03350 Genome accession   NZ_CP065707
Coordinates   653972..654925 (+) Length   317 a.a.
NCBI ID   WP_038804046.1    Uniprot ID   A0A7T3DZZ0
Organism   Streptococcus oralis strain FDAARGOS_885     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 648972..659925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G42_RS03305 (I6G42_03305) - 649149..649514 (+) 366 WP_000286399.1 DUF1033 family protein -
  I6G42_RS03310 (I6G42_03310) comGA/cglA/cilD 649584..650525 (+) 942 WP_038804053.1 competence type IV pilus ATPase ComGA Machinery gene
  I6G42_RS03315 (I6G42_03315) comGB/cglB 650473..651489 (+) 1017 WP_068981894.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6G42_RS03320 (I6G42_03320) comGC/cglC 651491..651814 (+) 324 WP_038804052.1 competence type IV pilus major pilin ComGC Machinery gene
  I6G42_RS03325 (I6G42_03325) comGD/cglD 651777..652211 (+) 435 WP_038804051.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6G42_RS03330 (I6G42_03330) comGE/cglE 652174..652476 (+) 303 WP_265101009.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6G42_RS03335 (I6G42_03335) comGF/cglF 652439..652900 (+) 462 WP_038804049.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6G42_RS03340 (I6G42_03340) comGG 652878..653290 (+) 413 Protein_646 competence type IV pilus minor pilin ComGG -
  I6G42_RS03345 (I6G42_03345) - 653323..653913 (+) 591 WP_038804047.1 class I SAM-dependent methyltransferase -
  I6G42_RS03350 (I6G42_03350) comYH 653972..654925 (+) 954 WP_038804046.1 class I SAM-dependent methyltransferase Machinery gene
  I6G42_RS03355 (I6G42_03355) - 654975..656165 (+) 1191 WP_038804045.1 acetate kinase -
  I6G42_RS03360 (I6G42_03360) rnpA 656325..656696 (+) 372 WP_000748124.1 ribonuclease P protein component -
  I6G42_RS03365 (I6G42_03365) - 656671..657483 (+) 813 WP_038804043.1 YidC/Oxa1 family membrane protein insertase -
  I6G42_RS03370 (I6G42_03370) jag 657501..658490 (+) 990 WP_038804042.1 RNA-binding cell elongation regulator Jag/EloR -
  I6G42_RS03375 (I6G42_03375) - 658542..659165 (+) 624 WP_038804041.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35583.87 Da        Isoelectric Point: 4.3184

>NTDB_id=513285 I6G42_RS03350 WP_038804046.1 653972..654925(+) (comYH) [Streptococcus oralis strain FDAARGOS_885]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKENNQALKRLALRKEEWLKTYQFLLMKAGQM
EPLQANHQFTPDAIALLLVLIVEELLHKEEISILEIGSGMGILGATFLISLAKKVDYLGIEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAIASRYQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKDEVSLAAIIALPEDIFSTASQAKSIFVLQKKRDKEIEPFVYPLTSLQDPAALLKFKENFQKWSKGTEM

Nucleotide


Download         Length: 954 bp        

>NTDB_id=513285 I6G42_RS03350 WP_038804046.1 653972..654925(+) (comYH) [Streptococcus oralis strain FDAARGOS_885]
ATGGATTTTGAAAAAATTGAACAAGCTTATACGTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTAGAGCAAAATAGTATCTACCTAGATGGTGAGACCGAATTAGAGCAGGTCAAGGAGAACAATC
AAGCTCTTAAACGCTTAGCGCTTCGCAAGGAAGAGTGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCAGGACAAATG
GAGCCTTTGCAGGCCAATCACCAGTTTACGCCGGATGCCATTGCCCTCCTCTTGGTACTTATTGTGGAAGAGTTGCTTCA
TAAAGAGGAAATTAGCATCCTCGAAATAGGTTCTGGAATGGGAATTCTGGGTGCTACTTTCTTGATATCTCTTGCTAAAA
AAGTAGATTACTTGGGAATTGAAGTGGATGATTTGCTGATTGATTTGGCGGCTAGTATGGCAGATGTGATCGGTTTGCAG
GCAGGATTTGTCCAAGGTGATGCCGTTCGTCCGCAAATGCTTAAAGAAAGCGATGTGGTCATTAGCGACTTGCCTGTTGG
CTATTACCCAGACGATGCCATCGCTTCACGCTATCAAGTGGCTTCTAGCCAAGAACATACCTATGCCCATCATTTGCTGA
TGGAGCAAGGCCTCAAGTACCTCAAGTCAGATGGCTATGCTATTTTTCTAGCTCCGAGCGACTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGGTTGGCTCAAAGACGAAGTGAGTCTGGCTGCTATCATCGCTCTGCCAGAGGATATTTTCTCAAC
TGCAAGCCAAGCTAAAAGTATTTTTGTCTTACAGAAGAAAAGAGACAAGGAAATAGAACCATTTGTCTATCCTTTGACCA
GTCTGCAAGATCCAGCTGCACTATTGAAATTCAAAGAAAATTTTCAAAAATGGAGCAAAGGTACTGAAATGTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DZZ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

58.521

98.107

0.574
  comYH Streptococcus mutans UA159

58.199

98.107

0.571