NTDB

Overview

Name	comGE/cglE	Type	Machinery gene
Locus tag	I6G42_RS03330	Genome accession	NZ_CP065707
Coordinates	652174..652476 (+)	Length	100 a.a.
NCBI ID	WP_265101009.1	Uniprot ID	-
Organism	Streptococcus oralis strain FDAARGOS_885
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 647174..657476

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G42_RS03300 (I6G42_03300)	nagA	647849..649000 (+)	1152	WP_038804054.1	N-acetylglucosamine-6-phosphate deacetylase	-
I6G42_RS03305 (I6G42_03305)	-	649149..649514 (+)	366	WP_000286399.1	DUF1033 family protein	-
I6G42_RS03310 (I6G42_03310)	comGA/cglA/cilD	649584..650525 (+)	942	WP_038804053.1	competence type IV pilus ATPase ComGA	Machinery gene
I6G42_RS03315 (I6G42_03315)	comGB/cglB	650473..651489 (+)	1017	WP_068981894.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6G42_RS03320 (I6G42_03320)	comGC/cglC	651491..651814 (+)	324	WP_038804052.1	competence type IV pilus major pilin ComGC	Machinery gene
I6G42_RS03325 (I6G42_03325)	comGD/cglD	651777..652211 (+)	435	WP_038804051.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6G42_RS03330 (I6G42_03330)	comGE/cglE	652174..652476 (+)	303	WP_265101009.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6G42_RS03335 (I6G42_03335)	comGF/cglF	652439..652900 (+)	462	WP_038804049.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6G42_RS03340 (I6G42_03340)	comGG	652878..653290 (+)	413	Protein_646	competence type IV pilus minor pilin ComGG	-
I6G42_RS03345 (I6G42_03345)	-	653323..653913 (+)	591	WP_038804047.1	class I SAM-dependent methyltransferase	-
I6G42_RS03350 (I6G42_03350)	comYH	653972..654925 (+)	954	WP_038804046.1	class I SAM-dependent methyltransferase	Machinery gene
I6G42_RS03355 (I6G42_03355)	-	654975..656165 (+)	1191	WP_038804045.1	acetate kinase	-
I6G42_RS03360 (I6G42_03360)	rnpA	656325..656696 (+)	372	WP_000748124.1	ribonuclease P protein component	-

Sequence

Protein

Download Length: 100 a.a. Molecular weight: 11149.14 Da Isoelectric Point: 8.6011

                                >NTDB_id=513283 I6G42_RS03330 WP_265101009.1 652174..652476(+) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_885]

MEKLNALRKLKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVRVNGVEIQVFS

SEKGLEVYHGSEQLLAIKEP

Nucleotide

Download Length: 303 bp

                                >NTDB_id=513283 I6G42_RS03330 WP_265101009.1 652174..652476(+) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_885]

ATGGAAAAATTAAACGCATTAAGGAAACTAAAAATTAGGGCAGTGATCTTACTAGAAGCAGTAGTAGCGCTAGCTATATT

TGCCAGTATTGCAACCCTCCTCTTGGGACAAATTCAGAAAAATAGACAAGAAGAGGCAGAAATCTTGCAAAAGGAAGAAG

TCTTACGTGTCGCTAAGATGGCCTTGCAGACGGGTCAAAATCAAGTGAGGGTAAATGGAGTGGAGATTCAGGTGTTTTCT

AGTGAAAAGGGATTGGAGGTTTATCATGGTTCAGAACAGTTGTTGGCTATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGE/cglE	Streptococcus pneumoniae TIGR4	96	100	0.96
comGE/cglE	Streptococcus pneumoniae Rx1	96	100	0.96
comGE/cglE	Streptococcus pneumoniae D39	96	100	0.96
comGE/cglE	Streptococcus pneumoniae R6	96	100	0.96
comGE/cglE	Streptococcus mitis SK321	95	100	0.95
comGE/cglE	Streptococcus mitis NCTC 12261	95	100	0.95
comYE	Streptococcus mutans UA140	41.111	90	0.37
comYE	Streptococcus mutans UA159	41.111	90	0.37

Detailed information NTG0513283