Detailed information NTG0513233

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: I6G43_RS07495
• Genome accession: NZ_CP065706
• Coordinates: 1556211..1556801 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613470.1
• Uniprot ID: A0A139PFB2
• Organism: Streptococcus oralis strain FDAARGOS_886
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1551211..1561801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G43_RS07470 (I6G43_07470)	-	1551904..1552668 (-)	765	WP_001186019.1	ABC transporter ATP-binding protein	-
I6G43_RS07475 (I6G43_07475)	-	1552668..1553624 (-)	957	WP_000856259.1	branched-chain amino acid ABC transporter permease	-
I6G43_RS07480 (I6G43_07480)	-	1553628..1554497 (-)	870	WP_000941414.1	branched-chain amino acid ABC transporter permease	-
I6G43_RS07485 (I6G43_07485)	-	1554616..1555776 (-)	1161	WP_000726138.1	ABC transporter substrate-binding protein	-
I6G43_RS07490 (I6G43_07490)	-	1555863..1556132 (-)	270	WP_000462110.1	YlbG family protein	-
I6G43_RS07495 (I6G43_07495)	clpP	1556211..1556801 (-)	591	WP_000613470.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
I6G43_RS07500 (I6G43_07500)	upp	1556975..1557604 (-)	630	WP_025168381.1	uracil phosphoribosyltransferase	-
I6G43_RS07505 (I6G43_07505)	-	1557693..1558160 (-)	468	WP_000136986.1	deoxycytidylate deaminase	-
I6G43_RS07510 (I6G43_07510)	-	1558179..1558736 (-)	558	WP_000003903.1	TetR/AcrR family transcriptional regulator	-
I6G43_RS07515 (I6G43_07515)	-	1558861..1559706 (+)	846	WP_000219944.1	DegV family protein	-
I6G43_RS07520 (I6G43_07520)	-	1559763..1560944 (+)	1182	WP_000680072.1	NAD(P)/FAD-dependent oxidoreductase	-
I6G43_RS07525 (I6G43_07525)	-	1560958..1561479 (+)	522	WP_009013910.1	DUF1697 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21348.39 Da
• Isoelectric Point: 4.5654

>NTDB_id=513233 I6G43_RS07495 WP_000613470.1 1556211..1556801(-) (clpP) [Streptococcus oralis strain FDAARGOS_886]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILATNSGK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNSLS

Nucleotide

• Length: 591 bp

>NTDB_id=513233 I6G43_RS07495 WP_000613470.1 1556211..1556801(-) (clpP) [Streptococcus oralis strain FDAARGOS_886]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGACATTTACTCTCGTCTTCTGAAAGACCGCAT
CATCATGCTAACTGGGCCAGTCGAAGATAATATGGCCAACTCAGTTATTGCCCAGTTGCTCTTCTTGGATGCCCAAGACA
GCACAAAAGATATTTACCTTTATGTCAACACACCTGGAGGTTCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACAATCGTTATGGGAATGGCTGCATCTATGGGGACTGTTATTGCATCAAGTGGTGCAAA
AGGCAAACGCTTCATGCTTCCAAATGCAGAGTACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAAA
CAGATATGGCAATCGCTGCAGAACACTTGCTCAAAACTCGTAAGACTTTGGAGCAAATCCTTGCGACTAACTCAGGTAAA
TCAGTTGAGCAAATTCATGCAGATGCTGAACGTGATTACTGGATGAGTGCCCAAGAAACGCTCGAATATGGCTTCATTGA
TGAAATCATGGCCAACAATTCTTTGAGCTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A139PFB2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	95.408	100	0.954
clpP	Streptococcus pneumoniae D39	95.408	100	0.954
clpP	Streptococcus pneumoniae R6	95.408	100	0.954
clpP	Streptococcus pneumoniae TIGR4	95.408	100	0.954
clpP	Streptococcus pyogenes MGAS315	92.308	99.49	0.918
clpP	Streptococcus pyogenes JRS4	92.308	99.49	0.918
clpP	Streptococcus thermophilus LMD-9	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	90.769	99.49	0.903
clpP	Streptococcus mutans UA159	88.205	99.49	0.878
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.179	99.49	0.867
clpP	Lactococcus lactis subsp. cremoris KW2	86.667	99.49	0.862
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	57.292	97.959	0.561