Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SPAF_RS07430 Genome accession   NC_017905
Coordinates   1495361..1496062 (-) Length   233 a.a.
NCBI ID   WP_014713657.1    Uniprot ID   I1ZN27
Organism   Streptococcus parasanguinis FW213     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1490361..1501062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPAF_RS07410 (Spaf_1476) rnc 1491893..1492594 (-) 702 WP_041826398.1 ribonuclease III -
  SPAF_RS07415 (Spaf_1477) - 1492694..1493080 (-) 387 WP_014713654.1 YbaN family protein -
  SPAF_RS07420 (Spaf_1478) vicX 1493199..1494008 (-) 810 WP_023918725.1 MBL fold metallo-hydrolase Regulator
  SPAF_RS07425 (Spaf_1479) micB 1494016..1495368 (-) 1353 WP_014713656.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SPAF_RS07430 (Spaf_1480) micA 1495361..1496062 (-) 702 WP_014713657.1 response regulator YycF Regulator
  SPAF_RS07435 (Spaf_1481) thrS 1496219..1498162 (-) 1944 WP_014713658.1 threonine--tRNA ligase -
  SPAF_RS07440 (Spaf_1482) - 1498516..1499838 (-) 1323 WP_014713659.1 glycosyltransferase family 4 protein -
  SPAF_RS07445 (Spaf_1483) - 1499840..1500838 (-) 999 WP_041826399.1 glycosyltransferase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26704.52 Da        Isoelectric Point: 4.6027

>NTDB_id=51142 SPAF_RS07430 WP_014713657.1 1495361..1496062(-) (micA) [Streptococcus parasanguinis FW213]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFVAENPDVIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQLENEADTEIVIGDLHILPDAFLVQKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=51142 SPAF_RS07430 WP_014713657.1 1495361..1496062(-) (micA) [Streptococcus parasanguinis FW213]
ATGAAAAAAATATTAGTAGTTGATGATGAAAAACCAATTTCAGACATTATCAAATTTAACATGGCGAAAGAGGGCTATGA
GGTATTGACAGCCTTTGATGGTCGGGAAGCATTGGAAGTCTTTGTAGCTGAAAATCCAGATGTTATTATTCTAGATTTGA
TGTTACCAGAGATTGATGGTTTAGAAGTGGCGCGGACGATTCGTAAGACCAGTAATGTGCCGATCATTGTCCTATCTGCC
AAAGATACGGAATTTGATAAGGTCATTGGGCTTGAAATTGGGGCAGATGACTATGTGACCAAACCCTTCTCGAATCGGGA
ATTGCAAGCGCGTGTGAAAGCCTTGTTGCGTCGTTCTGAGTTTGCGGCTGATCCTCAGCTTGAAAATGAAGCCGATACGG
AAATTGTCATTGGTGATCTTCACATTCTTCCAGATGCCTTCTTGGTTCAAAAAGGCAACAAAGAATTGGACTTGACTCAT
CGCGAATTTGAATTGCTCTATCACCTTGCGACCCATGTCGGTCAAGTGATGACCCGTGAGCACCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACAGTGGACGTGACGGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCGG
GACGTCCAGAATATATCTTGACTCGCCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I1ZN27

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

100

0.82
  vicR Streptococcus mutans UA159

78.298

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

98.712

0.455
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429
  scnR Streptococcus mutans UA159

36.957

98.712

0.365

Multiple sequence alignment