Detailed information NTG0051141

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: SPAF_RS07425
• Genome accession: NC_017905
• Coordinates: 1494016..1495368 (-)
• Length: 450 a.a.
• NCBI ID: WP_014713656.1
• Uniprot ID: I1ZN26
• Organism: Streptococcus parasanguinis FW213
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1489016..1500368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPAF_RS07410 (Spaf_1476)	rnc	1491893..1492594 (-)	702	WP_041826398.1	ribonuclease III	-
SPAF_RS07415 (Spaf_1477)	-	1492694..1493080 (-)	387	WP_014713654.1	YbaN family protein	-
SPAF_RS07420 (Spaf_1478)	vicX	1493199..1494008 (-)	810	WP_023918725.1	MBL fold metallo-hydrolase	Regulator
SPAF_RS07425 (Spaf_1479)	micB	1494016..1495368 (-)	1353	WP_014713656.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SPAF_RS07430 (Spaf_1480)	micA	1495361..1496062 (-)	702	WP_014713657.1	response regulator YycF	Regulator
SPAF_RS07435 (Spaf_1481)	thrS	1496219..1498162 (-)	1944	WP_014713658.1	threonine--tRNA ligase	-
SPAF_RS07440 (Spaf_1482)	-	1498516..1499838 (-)	1323	WP_014713659.1	glycosyltransferase family 4 protein	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51117.28 Da
• Isoelectric Point: 4.5621

>NTDB_id=51141 SPAF_RS07425 WP_014713656.1 1494016..1495368(-) (micB) [Streptococcus parasanguinis FW213]
MIDQLKQFVMSSNFVFVLITVGFIIVVALLLLENRRDNIKLRQLNSKIKDLIAGDYSEVVDMQGSPELTDMTNSINDLSE
VIRLTHENLEQETKRLTSILSYMTDGVLATNRRGQIIMVNEMAAKQLNVNPDEVLNTSILDLLSLGDDYDLRSLITEVPE
LTIDSQDENGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSQLDIELTNFTAFITFILNRFDKIKSQSQEDTKKYELIREYPITP
IWVEIDTDKMTQVIDNILNNAIKYSPDGGKIKVGMKTTDAQLIISISDEGLGIPKKDLPRIFDRFYRVDKARSRAQGGTG
LGLAIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAIKDDWDTEEEE

Nucleotide

• Length: 1353 bp

>NTDB_id=51141 SPAF_RS07425 WP_014713656.1 1494016..1495368(-) (micB) [Streptococcus parasanguinis FW213]
ATGATTGATCAACTAAAACAATTTGTAATGTCGTCGAATTTTGTCTTTGTTCTGATTACGGTTGGGTTTATCATTGTGGT
AGCCTTGCTTTTGCTAGAAAACCGTAGGGACAATATCAAGCTCAGACAATTAAACTCCAAAATTAAAGATCTGATTGCAG
GGGACTATTCAGAAGTGGTCGACATGCAAGGAAGTCCAGAACTGACGGATATGACCAATAGTATCAATGATCTGTCTGAG
GTTATTCGCCTGACGCATGAAAACTTGGAACAAGAAACCAAGCGTTTGACCAGTATCCTTTCTTACATGACAGATGGGGT
GCTTGCGACCAACAGACGCGGTCAGATCATCATGGTTAATGAAATGGCAGCCAAGCAATTGAATGTTAATCCAGATGAGG
TGCTCAATACCAGTATTCTAGATTTGCTTTCGCTTGGAGATGACTATGATCTGCGAAGCTTGATTACAGAAGTACCAGAG
TTGACCATCGATTCCCAGGATGAAAATGGGGAATACTTAAGTCTTCGTGTGCGCTTTGCCTTGATTCGTCGCGAGTCAGG
TTTTATCTCTGGTCTGGTAGCTGTCTTGCACGATACGACAGAGCAGGACAAGGAAGAACGGGAACGTCGCCTCTTTGTTT
CCAATGTGAGTCATGAATTACGGACACCGTTGACCAGTGTGAAATCCTATCTGGAAGCCCTAGACGATGGCGCTTTGTCA
GAGCCGGTAGCACCAGATTTTGTCAAGGTTTCACTCAATGAAACCAACCGCATGATGCGCATGGTCACAGATCTATTGAG
CTTGTCACGAATCGATAATGAAACCAGTCAGTTGGACATCGAGTTGACCAACTTTACGGCCTTTATCACCTTTATTTTGA
ACCGGTTTGATAAGATCAAGAGTCAATCGCAAGAAGATACTAAGAAGTATGAACTGATCCGGGAATACCCGATCACCCCG
ATCTGGGTTGAAATTGATACGGATAAAATGACCCAGGTGATCGACAATATCTTGAATAATGCCATCAAGTACTCACCTGA
TGGTGGAAAGATCAAGGTAGGGATGAAAACGACAGATGCCCAGTTGATTATCTCCATCTCAGATGAGGGCTTGGGAATTC
CCAAGAAAGACTTGCCTCGCATTTTTGATCGCTTTTACCGAGTGGATAAGGCACGTAGCCGGGCCCAAGGAGGGACTGGT
CTGGGCTTAGCCATTGCTAAGGAGATCGTTAAGCAACACAAAGGCTTTATTTGGGCCAAGAGTGAATATGGCAAGGGATC
TACCTTTACCATTGTCTTGCCGTACGACAAAGACGCTATTAAAGACGACTGGGATACAGAAGAGGAAGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (96-198)

3D structure

• AlphaFold DB: I1ZN26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	78.912	98	0.773
vicK	Streptococcus mutans UA159	71.007	90.444	0.642