Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SIR_RS17235 Genome accession   NC_022246
Coordinates   1541914..1542702 (-) Length   262 a.a.
NCBI ID   WP_003074456.1    Uniprot ID   T1ZG52
Organism   Streptococcus intermedius B196     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1536914..1547702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS17215 (SIR_1470) gatA 1537378..1538844 (-) 1467 WP_021003143.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SIR_RS17220 (SIR_1471) gatC 1538844..1539146 (-) 303 WP_021003144.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SIR_RS17225 (SIR_1472) aspS 1539211..1540959 (-) 1749 WP_021003145.1 aspartate--tRNA ligase -
  SIR_RS17230 (SIR_1473) - 1541339..1541914 (-) 576 WP_009569301.1 cysteine hydrolase family protein -
  SIR_RS17235 (SIR_1474) codY 1541914..1542702 (-) 789 WP_003074456.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SIR_RS17240 (SIR_1475) - 1542864..1544078 (-) 1215 WP_003074453.1 pyridoxal phosphate-dependent aminotransferase -
  SIR_RS17245 (SIR_1476) - 1544231..1544683 (+) 453 WP_003028799.1 universal stress protein -
  SIR_RS17250 (SIR_1477) - 1544729..1546117 (-) 1389 WP_021003146.1 Cof-type HAD-IIB family hydrolase -
  SIR_RS17255 (SIR_1478) - 1546182..1547144 (+) 963 WP_021003147.1 asparaginase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29694.03 Da        Isoelectric Point: 5.0797

>NTDB_id=51134 SIR_RS17235 WP_003074456.1 1541914..1542702(-) (codY) [Streptococcus intermedius B196]
MANLLAKTRKITSILRRSDERLQDELPYNAITQQLAEIMDCNACIVNSKGRLLGYFMRYKTNNDRVEAFYQTKIFPEEYV
RTANLMYDTEANLPVNHDLSIFPIEAKDEFPDGLTTISPIHVSGIRLGTLIVWRNDKEFDDDDLILVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELSGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLIPDIFEEIKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=51134 SIR_RS17235 WP_003074456.1 1541914..1542702(-) (codY) [Streptococcus intermedius B196]
ATGGCAAACTTATTAGCAAAAACAAGAAAAATAACATCTATTTTGCGTCGTTCAGATGAGCGGTTGCAGGATGAACTACC
TTATAATGCAATTACCCAACAATTAGCTGAAATTATGGATTGCAATGCTTGTATTGTAAATAGCAAGGGTCGTCTTTTGG
GGTATTTCATGCGCTACAAGACAAACAATGATCGTGTGGAAGCATTTTATCAAACGAAAATCTTCCCAGAAGAGTATGTT
CGCACCGCAAATTTGATGTATGATACTGAGGCCAATCTTCCAGTCAATCATGATTTATCTATTTTTCCTATTGAGGCAAA
AGATGAATTTCCAGATGGCTTGACGACAATTTCACCGATTCATGTTTCTGGGATTCGTTTAGGGACATTGATTGTTTGGC
GCAATGATAAAGAATTTGACGATGATGATTTGATCTTGGTTGAAATTGCAAGTACAGTGGTTGGTATTCAGCTACTCAAC
TTCCAACGAGAAGAAGATGAAAAAAATATTCGACGTCGAACAGCTGTAACTATGGCTGTAAATACTTTGTCTTATTCAGA
ATTACGAGCTGTTTCTGCTATTTTAGGTGAATTAAGCGGCAATGAAGGGCAGCTAACAGCTTCAGTGATTGCAGATCGTA
TTGGCATTACGCGCTCAGTGATTGTCAATGCTCTACGTAAACTAGAAAGTGCAGGCATTATCGAAAGTCGTTCTCTAGGA
ATGAAAGGAACCTATCTTAAAGTTCTTATCCCTGATATCTTTGAAGAGATTAAAAAGCGAGATTACTGA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

61.832

100

0.618
  codY Bacillus subtilis subsp. subtilis str. 168

50

93.893

0.469

Multiple sequence alignment