Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ST4147_RS00375 Genome accession   NZ_CP065504
Coordinates   62963..63148 (+) Length   61 a.a.
NCBI ID   WP_347229955.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4147     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 53449..63148 62963..63148 within 0


Gene organization within MGE regions


Location: 53449..63148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4147_RS00305 (ST4147_00305) - 53449..54615 (-) 1167 WP_347229946.1 site-specific integrase -
  ST4147_RS00310 (ST4147_00310) - 54690..55256 (-) 567 WP_347229947.1 helix-turn-helix transcriptional regulator -
  ST4147_RS00315 (ST4147_00315) - 55419..55616 (+) 198 WP_195950471.1 helix-turn-helix transcriptional regulator -
  ST4147_RS00320 (ST4147_00320) - 55873..56175 (+) 303 WP_347229948.1 hypothetical protein -
  ST4147_RS00325 (ST4147_00325) - 56180..56320 (+) 141 WP_347229949.1 hypothetical protein -
  ST4147_RS00330 (ST4147_00330) - 56401..56637 (+) 237 WP_347229959.1 hypothetical protein -
  ST4147_RS00335 (ST4147_00335) - 56654..56971 (+) 318 WP_347229950.1 hypothetical protein -
  ST4147_RS00340 (ST4147_00340) - 56973..57245 (+) 273 WP_232972846.1 MerR family transcriptional regulator -
  ST4147_RS00345 (ST4147_00345) - 57262..58119 (+) 858 WP_347229951.1 primase alpha helix C-terminal domain-containing protein -
  ST4147_RS00350 (ST4147_00350) - 58455..59528 (+) 1074 WP_232981333.1 virulence-associated E family protein -
  ST4147_RS00355 (ST4147_00355) - 59856..60038 (+) 183 WP_014727424.1 hypothetical protein -
  ST4147_RS00360 (ST4147_00360) - 60838..61308 (+) 471 WP_347229952.1 hypothetical protein -
  ST4147_RS00365 (ST4147_00365) - 61372..61908 (+) 537 WP_347229953.1 hypothetical protein -
  ST4147_RS00370 (ST4147_00370) - 62430..62639 (+) 210 WP_347229954.1 helix-turn-helix transcriptional regulator -
  ST4147_RS00375 (ST4147_00375) prx 62963..63148 (+) 186 WP_347229955.1 Paratox Regulator

Sequence

Protein


Download         Length: 61 a.a.        Molecular weight: 7147.21 Da        Isoelectric Point: 4.2558

>NTDB_id=511290 ST4147_RS00375 WP_347229955.1 62963..63148(+) (prx) [Streptococcus thermophilus strain 4147]
MLYYDELKEAIDRGFIKGDTVQIVKKNGIVFDYVLPNEPVKPYEVVTTERVADVLEELKEW

Nucleotide


Download         Length: 186 bp        

>NTDB_id=511290 ST4147_RS00375 WP_347229955.1 62963..63148(+) (prx) [Streptococcus thermophilus strain 4147]
ATGTTATATTATGATGAACTAAAAGAGGCAATCGATAGAGGTTTTATAAAGGGTGATACTGTTCAAATTGTGAAAAAGAA
TGGGATAGTATTTGATTATGTTCTCCCTAACGAACCAGTAAAGCCCTATGAGGTAGTTACTACTGAACGAGTAGCAGACG
TTTTGGAAGAGCTAAAAGAATGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

64.407

96.721

0.623
  prx Streptococcus pyogenes MGAS315

64.407

96.721

0.623
  prx Streptococcus pyogenes MGAS315

65.517

95.082

0.623
  prx Streptococcus pyogenes MGAS315

62.069

95.082

0.59
  prx Streptococcus pyogenes MGAS315

69.048

68.852

0.475
  prx Streptococcus pyogenes MGAS315

70.732

67.213

0.475
  prx Streptococcus pyogenes MGAS315

65.854

67.213

0.443