Detailed information NTG0511179

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STT128_RS01555
• Genome accession: NZ_CP065500
• Coordinates: 273583..274482 (+)
• Length: 299 a.a.
• NCBI ID: WP_002946143.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST128
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 268583..279482

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT128_RS01535 (STT128_01550)	trkA	269719..271068 (-)	1350	WP_084829332.1	Trk system potassium transporter TrkA	-
STT128_RS01540 (STT128_01555)	-	271357..271866 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
STT128_RS01545 (STT128_01560)	-	272178..272735 (+)	558	WP_002949523.1	ECF transporter S component	-
STT128_RS01550 (STT128_01565)	-	272738..273388 (+)	651	WP_084829333.1	phosphatase PAP2 family protein	-
STT128_RS01555 (STT128_01570)	comR	273583..274482 (+)	900	WP_002946143.1	helix-turn-helix domain-containing protein	Regulator
STT128_RS01560	-	274720..275898 (+)	1179	Protein_254	ABC transporter transmembrane domain-containing protein	-
STT128_RS01565	comA	275920..276129 (+)	210	WP_002946147.1	hypothetical protein	Regulator
STT128_RS01570 (STT128_01595)	-	276184..276752 (+)	569	Protein_256	ATP-binding cassette domain-containing protein	-
STT128_RS01575 (STT128_01600)	-	276860..277177 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
STT128_RS01580	-	277664..278560 (-)	897	WP_224102957.1	urease cluster protein	-
STT128_RS01585 (STT128_01610)	-	278965..279480 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35303.77 Da
• Isoelectric Point: 5.1073

>NTDB_id=511179 STT128_RS01555 WP_002946143.1 273583..274482(+) (comR) [Streptococcus thermophilus strain ST128]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=511179 STT128_RS01555 WP_002946143.1 273583..274482(+) (comR) [Streptococcus thermophilus strain ST128]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	99.666	100	0.997
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418