Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   STT128_RS00395 Genome accession   NZ_CP065500
Coordinates   64170..64358 (+) Length   62 a.a.
NCBI ID   WP_111679075.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST128     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 53468..65428 64170..64358 within 0


Gene organization within MGE regions


Location: 53468..65428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT128_RS00305 (STT128_00305) - 53468..54634 (-) 1167 WP_347230087.1 site-specific integrase -
  STT128_RS00310 (STT128_00310) - 54711..55295 (-) 585 WP_347230088.1 helix-turn-helix domain-containing protein -
  STT128_RS00315 (STT128_00315) - 55457..55654 (+) 198 WP_014727431.1 helix-turn-helix transcriptional regulator -
  STT128_RS00320 (STT128_00320) - 55872..56177 (+) 306 WP_347230089.1 hypothetical protein -
  STT128_RS00325 (STT128_00325) - 56181..56387 (+) 207 WP_022096594.1 hypothetical protein -
  STT128_RS00330 (STT128_00330) - 56401..56637 (+) 237 WP_023909301.1 hypothetical protein -
  STT128_RS00335 (STT128_00335) - 56624..56965 (+) 342 WP_347230090.1 hypothetical protein -
  STT128_RS00340 (STT128_00340) - 56967..57239 (+) 273 WP_023909303.1 MerR family transcriptional regulator -
  STT128_RS00345 (STT128_00345) - 57255..58115 (+) 861 WP_347230091.1 primase alpha helix C-terminal domain-containing protein -
  STT128_RS00350 (STT128_00350) - 58117..59613 (+) 1497 WP_347230178.1 phage/plasmid primase, P4 family -
  STT128_RS00355 (STT128_00355) - 59915..60100 (+) 186 WP_011681033.1 hypothetical protein -
  STT128_RS00360 (STT128_00360) - 60117..60392 (+) 276 WP_014608195.1 hypothetical protein -
  STT128_RS00365 (STT128_00365) - 60611..61060 (+) 450 WP_011681031.1 hypothetical protein -
  STT128_RS00370 (STT128_00370) - 61443..62030 (+) 588 WP_011681030.1 hypothetical protein -
  STT128_RS00375 (STT128_00375) - 62094..62624 (+) 531 WP_011681029.1 hypothetical protein -
  STT128_RS00380 (STT128_00380) - 62742..62948 (+) 207 WP_162484320.1 hypothetical protein -
  STT128_RS00385 (STT128_00385) - 63190..63399 (+) 210 Protein_55 transposase -
  STT128_RS00390 - 63478..63651 (+) 174 WP_347230092.1 hypothetical protein -
  STT128_RS00395 (STT128_00395) prx 64170..64358 (+) 189 WP_111679075.1 hypothetical protein Regulator
  STT128_RS00400 (STT128_00400) - 64739..65428 (+) 690 WP_197709066.1 DUF3800 domain-containing protein -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7133.08 Da        Isoelectric Point: 4.5837

>NTDB_id=511169 STT128_RS00395 WP_111679075.1 64170..64358(+) (prx) [Streptococcus thermophilus strain ST128]
MLTYDEFKEAMDNGFIKGDTVQIVRKNGKIHDYVLDGERVEPHEILRLEKVSDIIKELGGDN

Nucleotide


Download         Length: 189 bp        

>NTDB_id=511169 STT128_RS00395 WP_111679075.1 64170..64358(+) (prx) [Streptococcus thermophilus strain ST128]
ATGCTAACCTATGATGAATTTAAAGAGGCAATGGACAATGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGAAAGAA
TGGTAAGATCCATGACTACGTTTTAGACGGTGAACGAGTTGAGCCACACGAAATATTGAGATTAGAAAAAGTATCGGATA
TAATAAAAGAACTAGGCGGAGACAACTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

60.345

93.548

0.565
  prx Streptococcus pyogenes MGAS8232

59.322

95.161

0.565
  prx Streptococcus pyogenes MGAS315

57.627

95.161

0.548
  prx Streptococcus pyogenes MGAS315

56.897

93.548

0.532
  prx Streptococcus pyogenes MGAS315

74.419

69.355

0.516
  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5
  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5