Detailed information NTG0510940

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ST4021_RS01490
• Genome accession: NZ_CP065493
• Coordinates: 272030..272929 (+)
• Length: 299 a.a.
• NCBI ID: WP_011680720.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4021
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 267030..277929

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4021_RS01470 (ST4021_01465)	trkA	268167..269516 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
ST4021_RS01475 (ST4021_01470)	-	269805..270314 (+)	510	WP_011680717.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
ST4021_RS01480 (ST4021_01475)	-	270625..271182 (+)	558	WP_011680718.1	ECF transporter S component	-
ST4021_RS01485 (ST4021_01480)	-	271185..271835 (+)	651	WP_011680719.1	phosphatase PAP2 family protein	-
ST4021_RS01490 (ST4021_01485)	comR	272030..272929 (+)	900	WP_011680720.1	helix-turn-helix domain-containing protein	Regulator
ST4021_RS01495	-	273167..273748 (+)	582	Protein_241	cysteine peptidase family C39 domain-containing protein	-
ST4021_RS01500	comA	273733..274023 (+)	291	WP_194238295.1	ABC transporter transmembrane domain-containing protein	Regulator
ST4021_RS01505	comA	274366..274575 (+)	210	WP_002946147.1	hypothetical protein	Regulator
ST4021_RS01510 (ST4021_01505)	-	274630..275198 (+)	569	Protein_244	ATP-binding cassette domain-containing protein	-
ST4021_RS01515	-	275429..275617 (+)	189	WP_224103239.1	hypothetical protein	-
ST4021_RS01520	-	276110..276412 (-)	303	WP_224103194.1	hypothetical protein	-
ST4021_RS01525	-	276636..277007 (-)	372	WP_224103195.1	hypothetical protein	-
ST4021_RS01530 (ST4021_01520)	-	277413..277928 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35271.71 Da
• Isoelectric Point: 5.1073

>NTDB_id=510940 ST4021_RS01490 WP_011680720.1 272030..272929(+) (comR) [Streptococcus thermophilus strain 4021]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIVFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=510940 ST4021_RS01490 WP_011680720.1 272030..272929(+) (comR) [Streptococcus thermophilus strain 4021]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAATCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAGTGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMD-9	100	100	1
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.472	100	0.415