Detailed information NTG0510925

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ST4145_RS08685
• Genome accession: NZ_CP065492
• Coordinates: 1683369..1684469 (-)
• Length: 366 a.a.
• NCBI ID: WP_120764773.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4145
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1678369..1689469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4145_RS08640	-	1678694..1678969 (-)	276	WP_011681681.1	hypothetical protein	-
ST4145_RS08645 (ST4145_08570)	-	1678981..1679178 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
ST4145_RS08650 (ST4145_08575)	-	1679427..1680620 (-)	1194	WP_014608740.1	acetate kinase	-
ST4145_RS08655 (ST4145_08580)	comYH	1680676..1681632 (-)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
ST4145_RS08660 (ST4145_08585)	comGG	1681677..1681994 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
ST4145_RS08665 (ST4145_08590)	comYF	1681972..1682409 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST4145_RS08670 (ST4145_08595)	comGE	1682393..1682686 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST4145_RS08675 (ST4145_08600)	comYD	1682658..1683086 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST4145_RS08680 (ST4145_08605)	comYC	1683046..1683372 (-)	327	WP_014727724.1	competence type IV pilus major pilin ComGC	Machinery gene
ST4145_RS08685 (ST4145_08610)	comYB	1683369..1684469 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST4145_RS08690 (ST4145_08615)	comGA/cglA/cilD	1684351..1685292 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
ST4145_RS08695 (ST4145_08620)	-	1685373..1685735 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41876.03 Da
• Isoelectric Point: 10.1377

>NTDB_id=510925 ST4145_RS08685 WP_120764773.1 1683369..1684469(-) (comYB) [Streptococcus thermophilus strain 4145]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=510925 ST4145_RS08685 WP_120764773.1 1683369..1684469(-) (comYB) [Streptococcus thermophilus strain 4145]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413