Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   STT19_RS01450 Genome accession   NZ_CP065487
Coordinates   260439..261338 (+) Length   299 a.a.
NCBI ID   WP_011680720.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST19     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 255439..266338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT19_RS01430 (STT19_01430) trkA 256575..257924 (-) 1350 WP_014621137.1 Trk system potassium transporter TrkA -
  STT19_RS01435 (STT19_01435) - 258214..258723 (+) 510 WP_024704182.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  STT19_RS01440 (STT19_01440) - 259034..259591 (+) 558 WP_071417478.1 ECF transporter S component -
  STT19_RS01445 (STT19_01445) - 259594..260244 (+) 651 WP_071417477.1 phosphatase PAP2 family protein -
  STT19_RS01450 (STT19_01450) comR 260439..261338 (+) 900 WP_011680720.1 helix-turn-helix domain-containing protein Regulator
  STT19_RS01455 (STT19_01455) - 261576..262157 (+) 582 Protein_233 cysteine peptidase family C39 domain-containing protein -
  STT19_RS01460 (STT19_01460) comA 262142..262432 (+) 291 WP_194238295.1 ABC transporter transmembrane domain-containing protein Regulator
  STT19_RS01465 comA 262463..262606 (+) 144 WP_128887988.1 hypothetical protein Regulator
  STT19_RS01470 comA 262775..262984 (+) 210 WP_002946147.1 hypothetical protein Regulator
  STT19_RS01475 (STT19_01470) - 263039..263607 (+) 569 Protein_237 ATP-binding cassette domain-containing protein -
  STT19_RS01480 - 263838..264026 (+) 189 WP_224103239.1 hypothetical protein -
  STT19_RS01485 - 263994..264278 (-) 285 WP_232557103.1 hypothetical protein -
  STT19_RS01490 - 264519..264821 (-) 303 WP_224103194.1 hypothetical protein -
  STT19_RS01495 - 265045..265416 (-) 372 WP_224103195.1 hypothetical protein -
  STT19_RS01500 (STT19_01485) - 265822..266337 (+) 516 WP_002949547.1 AmiS/UreI family transporter -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35271.71 Da        Isoelectric Point: 5.1073

>NTDB_id=510581 STT19_RS01450 WP_011680720.1 260439..261338(+) (comR) [Streptococcus thermophilus strain ST19]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIVFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=510581 STT19_RS01450 WP_011680720.1 260439..261338(+) (comR) [Streptococcus thermophilus strain ST19]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAACTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTTTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAGTGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMD-9

100

100

1
  comR Streptococcus thermophilus LMG 18311

99.331

100

0.993
  comR Streptococcus salivarius strain HSISS4

94.649

100

0.946
  comR Streptococcus salivarius SK126

93.98

100

0.94
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.472

100

0.415