Detailed information NTG0510405

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STMM1_RS01525
• Genome accession: NZ_CP065484
• Coordinates: 276196..277095 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain MM1
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 271196..282095

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM1_RS01505 (STMM1_01500)	trkA	272333..273682 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
STMM1_RS01510 (STMM1_01505)	-	273971..274480 (+)	510	WP_024704182.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
STMM1_RS01515 (STMM1_01510)	-	274791..275348 (+)	558	WP_071417478.1	ECF transporter S component	-
STMM1_RS01520 (STMM1_01515)	-	275351..276001 (+)	651	WP_071417477.1	phosphatase PAP2 family protein	-
STMM1_RS01525 (STMM1_01520)	comR	276196..277095 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
STMM1_RS01530	-	277333..277764 (+)	432	Protein_248	cysteine peptidase family C39 domain-containing protein	-
STMM1_RS01535	-	277794..278459 (+)	666	Protein_249	ABC transporter transmembrane domain-containing protein	-
STMM1_RS01540	comA	278532..278741 (+)	210	WP_002946147.1	hypothetical protein	Regulator
STMM1_RS01545 (STMM1_01545)	-	278796..279364 (+)	569	Protein_251	ATP-binding cassette domain-containing protein	-
STMM1_RS01550 (STMM1_01550)	-	279472..279789 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
STMM1_RS01555	-	279752..280036 (-)	285	WP_014727318.1	hypothetical protein	-
STMM1_RS01560	-	280276..281172 (-)	897	WP_224102957.1	urease cluster protein	-
STMM1_RS01565 (STMM1_01560)	-	281577..282092 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=510405 STMM1_RS01525 WP_014607953.1 276196..277095(+) (comR) [Streptococcus thermophilus strain MM1]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=510405 STMM1_RS01525 WP_014607953.1 276196..277095(+) (comR) [Streptococcus thermophilus strain MM1]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418