Detailed information NTG0509951

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: ST4052_RS05225
• Genome accession: NZ_CP065476
• Coordinates: 997905..998612 (-)
• Length: 235 a.a.
• NCBI ID: WP_011227274.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4052
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 992905..1003612

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4052_RS05200 (ST4052_05285)	yidA	993256..994065 (+)	810	WP_011226081.1	sugar-phosphatase	-
ST4052_RS05205 (ST4052_05290)	-	994067..995281 (+)	1215	WP_011227270.1	aminoacyltransferase	-
ST4052_RS05210 (ST4052_05295)	-	995333..995694 (-)	362	Protein_970	YbaN family protein	-
ST4052_RS05215 (ST4052_05300)	vicX	995754..996566 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
ST4052_RS05220 (ST4052_05305)	vicK	996572..997912 (-)	1341	WP_011227273.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ST4052_RS05225 (ST4052_05310)	vicR	997905..998612 (-)	708	WP_011227274.1	response regulator YycF	Regulator
ST4052_RS05230 (ST4052_05315)	-	999143..999910 (+)	768	WP_347100829.1	amino acid ABC transporter ATP-binding protein	-
ST4052_RS05235 (ST4052_05320)	-	999922..1000755 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
ST4052_RS05240 (ST4052_05325)	-	1000773..1001471 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
ST4052_RS05245 (ST4052_05330)	-	1001483..1002133 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
ST4052_RS05250 (ST4052_05335)	endA	1002204..1003085 (-)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
ST4052_RS05255 (ST4052_05340)	-	1003147..1003335 (-)	189	WP_011227277.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27115.09 Da
• Isoelectric Point: 5.0130

>NTDB_id=509951 ST4052_RS05225 WP_011227274.1 997905..998612(-) (vicR) [Streptococcus thermophilus strain 4052]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEIVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=509951 ST4052_RS05225 WP_011227274.1 997905..998612(-) (vicR) [Streptococcus thermophilus strain 4052]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAATTGTCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	84.681	100	0.847
micA	Streptococcus pneumoniae Cp1015	79.399	99.149	0.787
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.136	100	0.383